catalog number :
MBS421947
products full name :
Goat anti-AGXT (rat) Antibody
products short name :
AGXT
products name syn :
Agxt; alanine-glyoxylate aminotransferase; Spat; Alanine-glyoxylate aminotransferase (Serine-pyruvate aminotransferase); Serine-pyruvate aminotransferase; angiotensin receptor 2; serine pyruvate aminotransferase precursor (AA -22 to 392); serine:pyruvate aminotransferase SPT; serine:pyruvate/alanine:glyoxylate aminotransferase; alanine-glyoxylate aminotransferase; Spat; Alanine-glyoxylate aminotransferase (Serine-pyruvate aminotransferase); Serine-pyruvate aminotransferase; angiotensin receptor 2; serine pyruvate aminotransferase precursor (AA -22 to 392); serine:pyruvate aminotransferase SPT; serine:pyruvate/alanine:glyoxylate aminotransferase
other names :
serine--pyruvate aminotransferase, mitochondrial; Serine--pyruvate aminotransferase, mitochondrial; serine--pyruvate aminotransferase; serine--pyruvate aminotransferase, mitochondrial; serine--pyruvate aminotransferase, peroxisomal; angiotensin receptor 2; serine-pyruvate aminotransferase; alanine--glyoxylate aminotransferase; serine:pyruvate aminotransferase SPT; serine:pyruvate/alanine:glyoxylate aminotransferase; alanine-glyoxylate aminotransferase; Alanine--glyoxylate aminotransferase (EC:2.6.1.44); AGT
products gene name :
AGXT
other gene names :
Agxt; Agxt; AGT; SPT; Spat; Agt1; SPT; AGT
uniprot entry name :
SPYA_RAT
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments gave an approx. 22kDa band in Mouse and Rat Liver lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 43.4kDa according to Rat NP_085914.1. The 22kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-DKAKSKVYSRKTK, from the internal region of the protein sequence according to NP_085914.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426920
ncbi acc num :
NP_085914.1
ncbi gb acc num :
NM_030656.1
ncbi mol weight :
43,399 Da
ncbi pathways :
Alanine And Aspartate Metabolism Pathway 198451!!Alanine, Aspartate And Glutamate Metabolism Pathway 101111!!Alanine, Aspartate And Glutamate Metabolism Pathway 100063!!Carbon Metabolism Pathway 816129!!Carbon Metabolism Pathway 817567!!Glycine, Serine And Threonine Metabolism Pathway 83342!!Glycine, Serine And Threonine Metabolism Pathway 313!!Glyoxylate And Dicarboxylate Metabolism Pathway 83394!!Glyoxylate And Dicarboxylate Metabolism Pathway 383!!Glyoxylate Metabolism Pathway 1010841
ncbi summary :
This gene encodes alanine-glyoxylate aminotransferase, which catalyzes the interconversion of L-alanine and glyoxylate to pyruvate and glycine. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. The longer transcript variant includes an upstream translation start codon and a downstream translation start codon. The upstream start codon initiates the translation of the mitochondrial enzyme precursor while the downstream start codon initiates the translation of the peroxisomal enzyme (see PMID:2332438). [provided by RefSeq, Feb 2013]