antibody

Goat anti-ABCD3 Antibody

MBS421942

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, mouse, rat

western blot, immunohistochemistry, enzyme immunoassay

Antibody

Goat anti-ABCD3 Antibody

ABCD3

ABCD3; ATP-binding cassette; sub-family D (ALD); member 3; ABC43; PMP70; PXMP1; ATP-binding cassette; sub-family D; member 3; Peroxisomal membrane protein-1 (70kD); dJ824O18.1 (ATP-binding cassette; sub-family D (ALD); member 3 (PMP70; PXMP1)); peroxisomal membrane protein 1 (70kD; Zellweger syndrome); ATP-binding cassette, sub-family D (ALD), member 3; ABC43; PMP70; PXMP1; ATP-binding cassette, sub-family D, member 3; Peroxisomal membrane protein-1 (70kD); dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1); peroxisomal membrane protein 1 (70kD, Zellweger syndrome)

ATP-binding cassette sub-family D member 3 isoform a; ATP-binding cassette sub-family D member 3; ATP-binding cassette sub-family D member 3; 70 kDa peroxisomal membrane protein; Peroxisomal membrane protein-1 (70kD); peroxisomal membrane protein 1 (70kD, Zellweger syndrome); dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); ATP-binding cassette, sub-family D (ALD), member 3; 70 kDa peroxisomal membrane protein; PMP70

ABCD3

ABCD3; ABCD3; ZWS2; ABC43; PMP70; PXMP1; PMP70; PXMP1; PMP70

ABCD3_HUMAN

Polyclonal

Goat

Human, Mouse, Rat

659

PDGREDQKRKGISD

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Immunohistochemistry: In paraffin embedded Human Testis shows vesicular staining in Sertoli cells. Recommended concentration, 2.5-3.8ug/ml. Western Blot: Approx. 70kDa band observed in Human Kidney lysates (calculated MW of 75.5kDa according to NP_002849.1). Recommended concentration: 0.2-0.6 ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.

Epitope: Internal Region. Immunogen: Peptide with sequence C-PDGREDQKRKGISD, from the internal region of the protein sequence according to NP_002849.1. Corresponding Immunizing Peptide: Catalog #MBS425530

Important Note: This antibody is expected to recognize one isoform (NP_002849.1) only.

4506341

NP_002849.1

NM_002858.3

27,121 Da

ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!ABCA Transporters In Lipid Homeostasis Pathway 477112!!Nuclear Receptors In Lipid Metabolism And Toxicity Pathway 198887!!Peroxisome Pathway 131226!!Peroxisome Pathway 131126!!Transmembrane Transport Of Small Molecules Pathway 106572

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD