antibody

Goat anti-ABCA4 (aa1336-49) Antibody

MBS421926

0.1 mg

225 USD

polyclonal

goat

nonconjugated

ELISA, enzyme immunoassay

Antibody

Goat anti-ABCA4 (aa1336-49) Antibody

ABCA4

ABCA4; ATP-binding cassette; sub-family A (ABC1); member 4; ABC10; ABCR; ARMD2; CORD3; DKFZp781N1972; FFM; FLJ17534; RMP; RP19; STGD; STGD1; ATP binding cassette transporter; ATP-binding cassette; sub-family A member 4; ATP-binding transporter; retina-specific; OTTHUMP00000012366; photoreceptor rim protein; retina-specific ABC transporter; Goat Anti-ABCA4; ATP-binding cassette, sub-family A (ABC1), member 4; ABC10; ABCR; ARMD2; CORD3; DKFZp781N1972; FFM; FLJ17534; RMP; RP19; STGD; STGD1; ATP binding cassette transporter; ATP-binding cassette, sub-family A member 4; ATP-binding transporter, retina-specific; OTTHUMP00000012366; photoreceptor rim protein; retina-specific ABC transporter

retinal-specific ATP-binding cassette transporter; Retinal-specific ATP-binding cassette transporter; retinal-specific ATP-binding cassette transporter; RIM protein; RIM ABC transporter; photoreceptor rim protein; stargardt disease protein; retina-specific ABC transporter; ATP binding cassette transporter; ATP-binding transporter, retina-specific; ATP-binding cassette sub-family A member 4; ATP-binding cassette transporter, retinal-specific; ATP-binding cassette, sub-family A (ABC1), member 4; ATP-binding cassette sub-family A member 4; RIM ABC transporter; RIM protein; RmP; Stargardt disease protein

ABCA4

ABCA4; ABCA4; FFM; RMP; ABCR; RP19; STGD; ABC10; ARMD2; CORD3; STGD1; ABCR; RIM protein; RmP

ABCA4_HUMAN

Polyclonal

Goat

Human

2273

EPECPGPQLNTGTQ

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA)

Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: Internal Region. Immunogen: Peptide with sequence EPECPGPQLNTGTQ, from the internal region of the protein sequence according to NP_000341.2.

Corresponding Immunizing Peptide: Catalog #MBS425337

105990541

NP_000341.2

NM_000350.2

255,944 Da

ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!Signal Transduction Pathway 477114!!The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway 771585!!Transmembrane Transport Of Small Molecules Pathway 106572!!Visual Phototransduction Pathway 771584

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Jul 2008]

0.1 mg

225 USD