antibody

Goat anti-MRP8 / ABCC11 Antibody

MBS421919

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, dog

western blot, enzyme immunoassay

Antibody

Goat anti-MRP8 / ABCC11 Antibody

MRP8/ABCC11

ABCC11; ATP-binding cassette transporter MRP8; ATP-binding cassette; sub-family C (CFTR/MRP); member 11; EWWD; MRP8; WW; ATP-binding cassette protein C11; ATP-binding cassette; sub-family C; member 11; multi-resistance protein 8; ATP-binding cassette transporter MRP8; ATP-binding cassette, sub-family C (CFTR/MRP), member 11; EWWD; MRP8; WW; ATP-binding cassette protein C11; ATP-binding cassette, sub-family C, member 11; multi-resistance protein 8

ATP-binding cassette sub-family C member 11 isoform a; ATP-binding cassette sub-family C member 11; ATP-binding cassette sub-family C member 11; multi-resistance protein 8; ATP-binding cassette protein C11; ATP-binding cassette transporter MRP8; multidrug resistance-associated protein 8; ATP-binding cassette transporter sub-family C member 11; ATP-binding cassette, sub-family C (CFTR/MRP), member 11; Multidrug resistance-associated protein 8

ABCC11

ABCC11; ABCC11; WW; EWWD; MRP8; MRP8

ABCCB_HUMAN

Polyclonal

Goat

Human, Dog

1382

KVVEFDRPEVLRK

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Approx. 125kDa band observed in Human Breast and Human Testis lysates (calculated MW of 150kDa according to NP_660187.1). Recommended concentration: 0.5-1.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: Internal Region (Near C Terminus). Immunogen: Peptide with sequence C-KVVEFDRPEVLRK, from the internal region (near C Terminus) of the protein sequence according to NP_115972.2; NP_660187.1. Corresponding Immunizing Peptide: Catalog #MBS426375

Important Note: This antibody is expected to recognize both reported isoforms (NP_115972.2; NP_660187.1). Reported variants represent identical protein (NP_115972.2; NP_149163.2).

21729873

NP_115972.2

NM_032583.3

150,093 Da

ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Transmembrane Transport Of Small Molecules Pathway 106572

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD