catalog number :
MBS421908
products full name :
Goat anti-MEST Antibody
products short name :
MEST
products name syn :
MEST; mesoderm specific transcript homolog (mouse); DKFZp686L18234; MGC111102; MGC8703; PEG1; mesoderm specific transcript; paternally expressed gene 1; MEST; mesoderm specific transcript homolog (mouse); DKFZp686L18234; MGC111102; MGC8703; PEG1; mesoderm specific transcript; paternally expressed gene 1
other names :
mesoderm-specific transcript homolog protein isoform a; Mesoderm-specific transcript homolog protein; mesoderm-specific transcript homolog protein; paternally-expressed gene 1 protein; mesoderm specific transcript; Paternally-expressed gene 1 protein
products gene name :
MEST
other gene names :
MEST; MEST; PEG1; PEG1
uniprot entry name :
MEST_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
QELLYRYKQNRSGR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 37kDa band observed in Mouse and Rat Testis lysates (calculated MW of 37.6kDa according to Human NP_803490.1 and 38.8kDa according to Rat NP_001009617.1). Recommended concentration: 0.2-0.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QELLYRYKQNRSGR, from the internal region of the protein sequence according to NP_002393.2; NP_803490.1. Corresponding Immunizing Peptide: Catalog #MBS425874
other info2 :
Important Note: This antibody is expected to recognize both reported isoforms (NP_002393.2; NP_803490.1). Reported variants NP_803490.1 and NP_803491.1 represent identical protein.
ncbi acc num :
NP_002393.2
ncbi gb acc num :
NM_002402.3
ncbi mol weight :
33,757 Da
ncbi summary :
This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]