catalog number :
MBS421904
products full name :
Goat anti-JAM2 / JAMB / CD322 Antibody
products short name :
JAM2/JAMB/CD322
products name syn :
JAM2; junctional adhesion molecule 2; C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM; JAM-IT/VE-JAM; OTTHUMP00000096100; junctional adhesion molecule B; vascular endothelial junction-associated molecule; Goat Anti-JAM2 / JAM-B; JAM2; junctional adhesion molecule 2; C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM; JAM-IT/VE-JAM; OTTHUMP00000096100; junctional adhesion molecule B; vascular endothelial junction-associated molecule
other names :
junctional adhesion molecule B isoform 1; Junctional adhesion molecule B; junctional adhesion molecule B; JAM-2; JAM-IT/VE-JAM; vascular endothelial junction-associated molecule; junctional adhesion molecule 2; Junctional adhesion molecule 2; JAM-2; Vascular endothelial junction-associated molecule; VE-JAM; CD_antigen: CD322
products gene name :
JAM2
other gene names :
JAM2; JAM2; JAMB; CD322; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43; C21orf43; VEJAM; JAM-B; JAM-2; VE-JAM
uniprot entry name :
JAM2_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 35kDa band observed in Human Heart lysates (calculated MW of 33.2kDa according to NP_067042.1). Recommended concentration: 0.5-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QRKGYFSKETSFQ, from the internal region of the protein sequence according to NP_067042.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426776
ncbi acc num :
NP_067042.1
ncbi gb acc num :
NM_021219.3
ncbi mol weight :
34,554 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cell Surface Interactions At The Vascular Wall Pathway 106062!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 83102!!Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway 515!!Extracellular Matrix Organization Pathway 576262!!Hemostasis Pathway 106028!!Integrin Cell Surface Interactions Pathway 106110!!Leukocyte Transendothelial Migration Pathway 83083!!Leukocyte Transendothelial Migration Pathway 494
ncbi summary :
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]