catalog number :
MBS421893
products full name :
Goat anti-SUMF1 Antibody
products short name :
SUMF1
products name syn :
SUMF1; sulfatase modifying factor 1; AAPA3037; FGE; MGC131853; MGC150436; C-alpha-formylglycine-generating enzyme; OTTHUMP00000115300; SUMF1; sulfatase modifying factor 1; AAPA3037; FGE; MGC131853; MGC150436; C-alpha-formylglycine-generating enzyme; OTTHUMP00000115300
other names :
sulfatase-modifying factor 1 isoform 1; Sulfatase-modifying factor 1; sulfatase-modifying factor 1; FGly-generating enzyme; C-alpha-formylglycine-generating enzyme 1; sulfatase modifying factor 1; C-alpha-formylglycine-generating enzyme 1
products gene name :
SUMF1
other gene names :
SUMF1; SUMF1; FGE; UNQ3037; AAPA3037; FGE
uniprot entry name :
SUMF1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
ETLNPKGPPSGKDR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 37-40kDa band observed in Mouse Pancreas, Mouse Eye and Human Kidney lysates (calculated MW of 40.6kDa according to Human NP_877437.2 and 40.6kDa according to Mouse NP_666049.2). Recommended concentration: 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-ETLNPKGPPSGKDR, from the internal region of the protein sequence according to NP_877437.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426423
ncbi acc num :
NP_877437.2
ncbi gb acc num :
NM_182760.3
ncbi mol weight :
38,386 Da
ncbi pathways :
Glycosphingolipid Metabolism Pathway 530751!!Lysosome Pathway 99052!!Lysosome Pathway 96865!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Metabolism Of Proteins Pathway 106230!!PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway 106231!!Post-translational Protein Modification Pathway 161012!!Sphingolipid Metabolism Pathway 119543!!The Activation Of Arylsulfatases Pathway 645291
ncbi summary :
This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]