catalog number :
MBS421853
products full name :
Goat anti-SEPT7 Antibody
products short name :
7-Sep
products name syn :
SEPT7; septin 7; CDC10; CDC3; Nbla02942; SEPT7A; CDC10 (cell division cycle 10; S. cerevisiae; homolog); CDC10 cell division cycle 10 homolog; cell division cycle 10; septin 7; CDC10; CDC3; Nbla02942; SEPT7A; CDC10 (cell division cycle 10, S. cerevisiae, homolog); CDC10 cell division cycle 10 homolog; cell division cycle 10
other names :
septin-7 isoform 1; Septin-7; septin-7; septin 7 variant 4; CDC10 protein homolog; CDC10 (cell division cycle 10, S. cerevisiae, homolog); septin 7; CDC10 protein homolog
products gene name :
7-Sep
other gene names :
SEPT7; SEPT7; CDC3; CDC10; SEPT7A; NBLA02942; CDC10
uniprot entry name :
SEPT7_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow, Horse
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 45kDa band observed in nuclear lysates of cell line HeLa (calculated MW of 50.7kDa according to NP_001779.3 and of 55.6kDa according to NP_001011553.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-DNNKNKGQLTKSP, from the internal region of the protein sequence according to NP_001779.3; NP_001011553.2; NP_001229885.1. Corresponding Immunizing Peptide: Catalog #MBS426798
other info2 :
Important Note: This antibody is expected to recognize all three reported isoforms (NP_001779.3; NP_001011553.2; NP_001229885.1).
ncbi acc num :
NP_001779.3
ncbi gb acc num :
NM_001788.5
ncbi mol weight :
50,581 Da
ncbi summary :
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]