This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-CHRNA4 (aa29-43) Antibody
catalog :
MBS421841
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, enzyme immunoassay
product information
catalog number :
MBS421841
products type :
Antibody
products full name :
Goat anti-CHRNA4 (aa29-43) Antibody
products short name :
CHRNA4
products name syn :
CHRNA4; cholinergic receptor; nicotinic; alpha 4; BFNC; EBN; EBN1; NACRA4; cholinergic receptor; nicotinic; alpha 4 subunit; cholinergic receptor; nicotinic; alpha polypeptide 4; neuronal acetylcholine receptor alpha 4 subunit; neuronal nicotinic acetylcholine receptor alpha-4 subunit; Goat Anti-CHRNA4; CHRNA4; cholinergic receptor, nicotinic, alpha 4; BFNC; EBN; EBN1; NACRA4; cholinergic receptor, nicotinic, alpha 4 subunit; cholinergic receptor, nicotinic, alpha polypeptide 4; neuronal acetylcholine receptor alpha 4 subunit; neuronal nicotinic acetylcholine receptor alpha-4 subunit
other names :
neuronal acetylcholine receptor subunit alpha-4 isoform 1; Neuronal acetylcholine receptor subunit alpha-4; neuronal acetylcholine receptor subunit alpha-4; cholinergic receptor, nicotinic, alpha polypeptide 4; neuronal nicotinic acetylcholine receptor alpha-4 subunit; cholinergic receptor, nicotinic, alpha 4 (neuronal)
products gene name :
CHRNA4
other gene names :
CHRNA4; CHRNA4; EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4; NACRA4
uniprot entry name :
ACHA4_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence length :
627
sequence :
HVETRAHAEERLLKK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 70kDa band observed in Rat Brain lysates (calculated MW of 70.0kDa according to Human NP_000735.1and of 70.2kDa according to Rat NP_077330.1). Recommended concentration: 1-3ug/ml. An additional band of unknown identity was also consistently observed at 22kDa. This band was successfully blocked by incubation with the immunising peptide. ~75kDa confirmed in both human and rat tissues as the glycoprotein by an anonymous customer. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-HVETRAHAEERLLKK, from the internal region of the protein sequence according to NP_000735.1. Corresponding Immunizing Peptide: Catalog #MBS426962
other info2 :
Important Note: This antibody is expected NOT to cross-react with the similar alpha 2 subunit.
ncbi gi num :
4502827
ncbi acc num :
NP_000735.1
ncbi gb acc num :
NM_000744.6
ncbi mol weight :
60,994 Da
ncbi pathways :
Acetylcholine Binding And Downstream Events Pathway 106535!!Activation Of Nicotinic Acetylcholine Receptors Pathway 161027!!Cholinergic Synapse Pathway 217716!!Highly Calcium Permeable Nicotinic Acetylcholine Receptors Pathway 161029!!Highly Calcium Permeable Postsynaptic Nicotinic Acetylcholine Receptors Pathway 161032!!Highly Sodium Permeable Acetylcholine Nicotinic Receptors Pathway 161030!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462!!Neuronal System Pathway 106513!!Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway 106534
ncbi summary :
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!