Goat anti-CAMK2A Antibody | MyBioSource MBS421825 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-CAMK2A Antibody

catalog :

MBS421825

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog

application :

western blot, immunohistochemistry, enzyme immunoassay

product information

catalog number :

MBS421825

products type :

Antibody

products full name :

Goat anti-CAMK2A Antibody

products short name :

CAMK2A

products name syn :

CAMK2A; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; CAMKA; KIAA0968; CaM kinase II alpha subunit; CaM-kinase II alpha chain; CaMK-II alpha subunit; OTTHUMP00000165787; OTTHUMP00000165788; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase IIA; calcium/calmodulin-dependent protein kinase type II alpha chain; CAMK2A; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; CAMKA; KIAA0968; CaM kinase II alpha subunit; CaM-kinase II alpha chain; CaMK-II alpha subunit; OTTHUMP00000165787; OTTHUMP00000165788; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase IIA; calcium/calmodulin-dependent protein kinase type II alpha chain

other names :

calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 1; Calcium/calmodulin-dependent protein kinase type II subunit alpha; calcium/calmodulin-dependent protein kinase type II subunit alpha; CaMKIINalpha; CaMK-II alpha subunit; caMK-II subunit alpha; CaM-kinase II alpha chain; CaM kinase II alpha subunit; caM kinase II subunit alpha; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase II alpha

products gene name :

CAMK2A

other gene names :

CAMK2A; CAMK2A; CAMKA; CAMKA; KIAA0968; CaM kinase II subunit alpha; CaMK-II subunit alpha

uniprot entry name :

KCC2A_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human, Mouse, Rat, Dog

sequence length :

489

sequence :

PRTAQSEETRVWHR

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Immunohistochemistry: In paraffin embedded Human Brain Cortex shows granular staining in the periphery of pyramydal cell bodies. Recommended concentration, 3-6ug/ml. Western Blot: Approx 55+65kDa bands observed in Human Brain (Cerebellum) and Mouse Brain lysates (calculated MW of 55.3kDa according to Human NP_057065.2 and of 54.1 according to Human NP_741960.1 and Mouse NP_803126.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.

other info1 :

Epitope: Internal Region. Immunogen: Peptide with sequence C-PRTAQSEETRVWHR, from the internal region of the protein sequence according to NP_057065.2; NP_741960.1. Corresponding Immunizing Peptide: Catalog #MBS426892

other info2 :

Important Note: This antibody is expected to recognize both reported isoforms (NP_057065.2; NP_741960.1).

ncbi gi num :

25952114

ncbi acc num :

NP_057065.2

ncbi gb acc num :

NM_015981.3

ncbi mol weight :

55,320 Da

ncbi pathways :

Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway 161033!!Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Amphetamine Addiction Pathway 547607!!Amphetamine Addiction Pathway 550546!!BDNF Signaling Pathway 712093!!CREB Phosphorylation Through The Activation Of CaMKII Pathway 161040!!CREB Phosphorylation Through The Activation Of Ras Pathway 161036!!Ca2+ Pathway 941399!!Calcium Regulation In The Cardiac Cell Pathway 198906

ncbi summary :

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]

size :

0.1 mg

price :

290 USD