catalog number :
MBS421824
products full name :
Goat anti-FBN1 Antibody
products short name :
FBN1
products name syn :
FBN1; fibrillin 1; FBN; MASS; MFS1; OCTD; SGS; WMS; fibrillin 15; FBN1; fibrillin 1; FBN; MASS; MFS1; OCTD; SGS; WMS; fibrillin 15
other names :
fibrillin 1; Fibrillin-1; fibrillin-1; fibrillin 15; fibrillin 1
products gene name :
FBN1
other gene names :
FBN1; FBN1; FBN; SGS; WMS; MASS; MFS1; OCTD; SSKS; WMS2; ACMICD; ECTOL1; GPHYSD2; FBN
uniprot entry name :
FBN1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
DASNIEDQSETEAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments in Human Brain (Cerebellum), Heart, Kidney, Skeletal Muscle and Skin lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Peptide ELISA: antibody detection limit dilution 1:2000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-DASNIEDQSETEAN, from the Internal region of the protein sequence according to NP_000129.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426834
ncbi acc num :
NP_000129.2
ncbi gb acc num :
NM_000138.3
ncbi mol weight :
312,237 Da
ncbi pathways :
Elastic Fibre Formation Pathway 730310!!Extracellular Matrix Organization Pathway 576262!!Integrin Cell Surface Interactions Pathway 106110
ncbi summary :
This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq, Jul 2008]