catalog number :
MBS421820
products full name :
Goat anti-AADAT Antibody
products short name :
AADAT
products name syn :
AADAT; aminoadipate aminotransferase; KAT2; KATII; L kynurenine/alpha aminoadipate aminotransferase; L-kynurenine/alpha-aminoadipate aminotransferase; alpha-aminoadipate aminotransferase; kynurenine aminotransferase II; Goat Anti-AADAT (int.); aminoadipate aminotransferase; KAT2; KATII; L kynurenine/alpha aminoadipate aminotransferase; L-kynurenine/alpha-aminoadipate aminotransferase; alpha-aminoadipate aminotransferase; kynurenine aminotransferase II
other names :
vacuolar protein sorting-associated protein 29 isoform 1; Vacuolar protein sorting-associated protein 29; vacuolar protein sorting-associated protein 29; hVPS29; PEP11 homolog; x 007 protein; retromer protein; vesicle protein sorting 29; vacuolar sorting protein VPS29/PEP11; vacuolar protein sorting 29 homolog (S. cerevisiae); PEP11 homolog; Vesicle protein sorting 29
products gene name :
AADAT
other gene names :
VPS29; VPS29; DC7; DC15; PEP11; hVPS29
uniprot entry name :
VPS29_HUMAN
sequence :
KPEDAKNPQKNTPK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 45kDa band observed in Human Liver lysates (calculated MW of 47.4kDa according to NP_057312.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-KPEDAKNPQKNTPK, from the internal region of the protein sequence according to NP_057312.1; NP_872603.1. Corresponding Immunizing Peptide: Catalog #MBS426425
other info2 :
Important Note: Both reported variants represent identical protein (NP_057312.1and NP_872603.1).
ncbi acc num :
NP_057310.1
ncbi gb acc num :
NM_016226.4
ncbi mol weight :
20,927 Da
ncbi pathways :
Disease Pathway 530764!!Signal Transduction Pathway 477114!!Signaling By WNT In Cancer Pathway 1016191!!Signaling By Wnt Pathway 106510!!WNT Ligand Biogenesis And Trafficking Pathway 833832!!WNT Ligand Secretion Is Abrogated By The PORCN Inhibitor LGK974 Pathway 1016211
ncbi summary :
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013]