catalog number :
MBS421788
products full name :
Goat anti-TROP2 Antibody
products short name :
TROP2
products name syn :
TROP2; TACSTD2; tumor-associated calcium signal transducer 2; EGP-1; GA733; GA733-1; M1S1; epithelial glycoprotein-1; membrane component, chromosome 1, surface marker 1 (40kD glycoprotein, identified by monoclonal antibody GA733); TROP2 antibody; TACSTD2 antibody; tumor-associated calcium signal transducer 2 antibody; EGP-1 antibody; GA733 antibody; GA733-1 antibody; M1S1 antibody; epithelial glycoprotein-1 antibody; membrane component; chromosome 1; surface marker 1 (40kD glycoprotein; identified by monoclonal antibody GA733) antibody
other names :
tumor-associated calcium signal transducer 2; Tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1
products gene name :
TACSTD2
products gene name syn :
TROP2
other gene names :
TACSTD2; TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; GA733-1; M1S1; TROP2
uniprot entry name :
TACD2_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
sequence :
HYEQPTIQIELRQN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 4000. Western Blot: Approx.37kDa band observed in Human Prostate lysates (calculated MW of 35.7kDa according to NP_002344.2). Recommended concentration: 0.2-0.5ug/ml.
other info1 :
Immunogen: Peptide with sequence C-HYEQPTIQIELRQN, from the internal region of the protein sequence according to NP_002344.2. Epitope: Internal region
ncbi acc num :
NP_002344.2
ncbi gb acc num :
NM_002353.2
ncbi mol weight :
35,709 Da
ncbi summary :
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]
uniprot summary :
TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1p32. Cellular Component: basal plasma membrane; cytosol; extracellular space; integral to plasma membrane; lateral plasma membrane; membrane; nucleus. Molecular Function: protein binding; receptor activity. Biological Process: cell proliferation; cell surface receptor linked signal transduction; negative regulation of stress fiber formation; regulation of epithelial cell proliferation; visual perception. Disease: Corneal Dystrophy, Gelatinous Drop-like