product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-SRCAP Antibody
catalog :
MBS421768
quantity :
0.1 mg
price :
225 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421768
products type :
Antibody
products full name :
Goat anti-SRCAP Antibody
products short name :
SRCAP
products name syn :
Goat Anti-SRCAP (aa309-322) Antibody; SRCAP; Snf2-related CREBBP activator protein; DOMO1; EAF1; FLJ44499; KIAA0309; SWR1; OTTHUMP00000163226; Snf2-related CBP activator protein; Swi2/Snf2-related ATPase homolog, domino homolog 1; SRCAP antibody; Snf2-related CREBBP activator protein antibody; DOMO1 antibody; EAF1 antibody; FLJ44499 antibody; KIAA0309 antibody; SWR1 antibody; OTTHUMP00000163226 antibody; Snf2-related CBP activator protein antibody; Swi2/Snf2-related ATPase homolog; domino homolog 1 antibody
other names :
helicase SRCAP; Helicase SRCAP; helicase SRCAP; Snf2-related CREBBP activator protein; Domino homolog 2; Snf2-related CBP activator
products gene name :
SRCAP
other gene names :
SRCAP; SRCAP; EAF1; FLHS; SWR1; DOMO1; KIAA0309
uniprot entry name :
SRCAP_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Expected from sequence similarity: Human, Mouse, Rat, Dog
sequence length :
3230
sequence :
DEAQNIKNFKSQR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 8000. Western Blot: Preliminary experiments in lysates of cell lines K562 and MOLT4 gave no specific signal but low background (at antibody concentration up to 1ug/ml).
other info1 :
Immunogen: Peptide with sequence C-DEAQNIKNFKSQR, from the internal region of the protein sequence according to NP_006653.2. Epitope: Internal region
ncbi gi num :
146219843
ncbi acc num :
NP_006653.2
ncbi gb acc num :
NM_006662.2
ncbi mol weight :
327,838 Da
ncbi summary :
This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012]
uniprot summary :
SRCAP: Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription. Defects in SRCAP are the cause of Floating-Harbor syndrome (FLHS). A rare genetic disorder characterized by proportionate short stature, delayed bone age, delayed speech development, and typical facial features. The face is triangular with deep-set eyes, long eyelashes, bulbous nose, wide columella, short philtrum, and thin lips. Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.6.4.-; Transcription, coactivator/corepressor; Helicase; EC 3.6.1.-; DNA-binding; Acetyltransferase. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: Golgi apparatus; nucleus; perinuclear region of cytoplasm; protein complex. Molecular Function: ATP binding; DNA binding; helicase activity; histone acetyltransferase activity; protein binding; transcription coactivator activity. Biological Process: histone acetylation; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; viral reproduction. Disease: Floating-harbor Syndrome
size1 :
0.1 mg
price1 :
225 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!