catalog number :
MBS421749
products full name :
Goat anti-TGFBI Antibody
products short name :
TGFBI
products name syn :
BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; kerato-epithelin; LCD1; RGD-containing collagen-associated protein; transforming growth factor; beta-induced; 68kDa; TGFBI; TGFBI; transforming growth factor, beta-induced, 68kDa; BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1; RGD-containing collagen-associated protein; kerato-epithelin
other names :
transforming growth factor-beta-induced protein ig-h3; Transforming growth factor-beta-induced protein ig-h3; transforming growth factor-beta-induced protein ig-h3; RGD-CAP; beta ig-h3; kerato-epithelin; RGD-containing collagen-associated protein; transforming growth factor, beta-induced, 68kD; transforming growth factor, beta-induced, 68kDa; Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP
products gene name :
TGFBI
other gene names :
TGFBI; TGFBI; CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1; BIGH3; Beta ig-h3; RGD-CAP
uniprot entry name :
BGH3_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Kidney shows staining of intercalated cells of a collecting tubule. Recommended concentration, 4-6ug/ml. Western Blot: Approx 70kDa band observed in Human, Mouse and Rat Kidney lysates (calculated MW of 74.7kDa according to Human NP_000349.1). Recommended concentration: 0.2-0.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QLYTDRTEKLRPE, from the internal region of the protein sequence according to NP_000349.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426158
ncbi acc num :
NP_000349.1
ncbi gb acc num :
NM_000358.2
ncbi mol weight :
74,681 Da
ncbi pathways :
Amyloids Pathway 366238!!Disease Pathway 530764
ncbi summary :
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]