Goat anti-TAF8/TAFII43 Antibody | MyBioSource MBS421722 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-TAF8/TAFII43 Antibody

catalog :

MBS421722

quantity :

0.1 mg

price :

225 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS421722

products type :

Antibody

products full name :

Goat anti-TAF8/TAFII43 Antibody

products short name :

TAF8/TAFII43

products name syn :

TAF8; TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa; 43; FLJ32821; II; TAF; TAFII43; TBN; OTTHUMP00000016392; TAF(II)43; TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50 kD; TATA box binding pr; TAF8 antibody; TAF8 RNA polymerase II; TATA box binding protein (TBP)-associated factor; 43kDa antibody; 43 antibody; FLJ32821 antibody; II antibody; TAF antibody; TAFII43 antibody; TBN antibody; OTTHUMP00000016392 antibody; TAF(II)43 antibody; TAF8 RNA polymerase II; TATA box binding protein (TBP)-associated factor; 50 kD antibody; TATA box binding protein (TBP)-associated factor; RNA polymerase II; A; 45/50kDa antibody; TBP-associated factor 8 antibody; TBP-associated factor TAFII43 antibody; TBP-associated factor; RNA polymerase II; 43 kD antibody; taube nuss homolog antibody; TAF8 / TAFII43

other names :

transcription initiation factor TFIID subunit 8; Transcription initiation factor TFIID subunit 8; transcription initiation factor TFIID subunit 8; TATA-box binding protein associated factor 8; Protein taube nuss; TBP-associated factor 43 kDa; TBP-associated factor 8; Transcription initiation factor TFIID 43 kDa subunit; TAFII-43; TAFII43; hTAFII43

products gene name :

TAF8

products gene name syn :

TAFII43

other gene names :

TAF8; TAF8; II; TAF; TBN; TAFII43; TAFII-43; TAFII43; TBN; TAFII-43; TAFII43; hTAFII43

uniprot entry name :

TAF8_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow

sequence length :

310

sequence :

KSYCEHTARTQPT

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Preliminary experiments gave an approx 38kDa band in Human Brain (Amygdala, Cerebellum, Hippocampus) lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 34.3kDa according to NP_612639.2. The 38kDa band was successfully blocked by incubation with the immunizing peptide.

other info1 :

Immunogen: Peptide with sequence KSYCEHTARTQPT, from the internal region of the protein sequence according to NP_612639.2. Epitope: Internal region

ncbi gi num :

104485446

ncbi acc num :

NP_612639.2

ncbi gb acc num :

NM_138572.2

ncbi mol weight :

37,411 Da

ncbi pathways :

Basal Transcription Factors Pathway (83038); Basal Transcription Factors Pathway (443); Gene Expression Pathway (1269649); RNA Polymerase II Transcribes SnRNA Genes Pathway (1383088)

ncbi summary :

This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

uniprot summary :

TBN: Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts. Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell mass which constitute the pluripotent cell population of the early embryo. Belongs to the TAF8 family. 3 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 6p21.1. Cellular Component: nucleoplasm; nucleus; perinuclear region of cytoplasm; transcription factor TFIID complex. Molecular Function: protein binding; protein heterodimerization activity. Biological Process: cell differentiation; inner cell mass cell proliferation; maintenance of protein localization in nucleus; positive regulation of transcription, DNA-dependent; regulation of fat cell differentiation; snRNA transcription from RNA polymerase II promoter

size1 :

0.1 mg

price1 :

225 USD

more info or order :

MyBioSource product webpage