catalog number :
MBS421720
products full name :
Goat anti-Connexin 43 / GJA1 Antibody
products short name :
Connexin 43/GJA1
products name syn :
GJA1; gap junction protein; alpha 1; 43kDa; CX43; DFNB38; GJAL; ODDD; connexin 43; gap junction 43 kDa heart protein; gap junction protein; alpha-like; GJA1; gap junction protein, alpha 1, 43kDa; CX43; DFNB38; GJAL; ODDD; connexin 43; gap junction 43 kDa heart protein; gap junction protein, alpha-like
other names :
gap junction alpha-1 protein; Gap junction alpha-1 protein; gap junction alpha-1 protein; connexin 43; connexin-43; gap junction 43 kDa heart protein; gap junction protein, alpha 1, 43kDa; Connexin-43; Cx43; Gap junction 43 kDa heart protein
products gene name :
GJA1
other gene names :
GJA1; GJA1; HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1; GJAL; Cx43
uniprot entry name :
CXA1_HUMAN
reactivity :
Human, Rat, Dog, Pig
sequence :
QPFDFPDDNQNSKK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 40kDa band observed in Rat Brain lysates (calculated MW of 43.0kDa according to Human NP_000156.1 and to Rat NP_036699.1). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QPFDFPDDNQNSKK, from the internal region of the protein sequence according to NP_000156.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426386
ncbi acc num :
NP_000156.1
ncbi gb acc num :
NM_000165.4
ncbi mol weight :
43,008 Da
ncbi pathways :
Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Corticotropin-releasing Hormone Pathway 920957!!EGFR1 Signaling Pathway 198782!!Formation Of Annular Gap Junctions Pathway 105934!!Gap Junction Pathway 83072!!Gap Junction Pathway 483!!Gap Junction Assembly Pathway 105928
ncbi summary :
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]