Goat anti-CCL20 Antibody | MyBioSource MBS421719 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-CCL20 Antibody

catalog :

MBS421719

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, cow

application :

immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS421719

products type :

Antibody

products full name :

Goat anti-CCL20 Antibody

products short name :

CCL20

products name syn :

CCL20; chemokine (C-C motif) ligand 20; CKb4; LARC; MIP-3a; MIP3A; SCYA20; ST38; exodus-1; macrophage inflammatory protein 3 alpha; small inducible cytokine subfamily A (Cys-Cys), member 20; CCL20 antibody; chemokine (C-C motif) ligand 20 antibody; CKb4 antibody; LARC antibody; MIP-3a antibody; MIP3A antibody; SCYA20 antibody; ST38 antibody; exodus-1 antibody; macrophage inflammatory protein 3 alpha antibody; small inducible cytokine subfamily A (Cys-Cys); member 20 antibody

other names :

C-C motif chemokine 20 isoform 1; C-C motif chemokine 20; C-C motif chemokine 20; C-C motif chemokine ligand 20; Beta-chemokine exodus-1; CC chemokine LARC; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP-3-alpha

products gene name :

CCL20

other gene names :

CCL20; CCL20; CKb4; LARC; ST38; MIP3A; Exodus; MIP-3a; SCYA20; MIP-3-alpha; LARC; MIP3A; SCYA20; MIP-3-alpha

uniprot entry name :

CCL20_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human, Cow, Pig

sequence length :

sequence :

CLGYTDRILHPK

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Immunohistochemistry (IHC)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 16000. Immunohistochemistry: In paraffin embedded Human Liver shows local staining between the hepatocytes. Recommended concentration, 6-8ug/ml. Western Blot: Preliminary experiments in Human Peripheral Blood Mononucleocytes lysates gave no specific signal but low background (at antibody concentration up to 2ug/ml).

other info1 :

Immunogen: Peptide with sequence CLGYTDRILHPK, from the internal region of the protein sequence according to NP_004582.1; NP_001123518.1. Epitope: Internal region

other info2 :

Note: This antibody is expected to recognize both isoforms (NP_004582.1; NP_001123518.1).

ncbi gi num :

4759076

ncbi acc num :

NP_004582.1

ncbi gb acc num :

NM_004591.2

ncbi mol weight :

10,691 Da

ncbi pathways :

Chemokine Receptors Bind Chemokines Pathway (1269547); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); EBV LMP1 Signaling Pathway (198790); G Alpha (i) Signalling Events Pathway (1269576); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544)

ncbi summary :

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

uniprot summary :

CCL20: Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Chemokine. Chromosomal Location of Human Ortholog: 2q36.3. Cellular Component: extracellular region; extracellular space. Molecular Function: CCR chemokine receptor binding; chemokine activity; protein binding. Biological Process: cell-cell signaling; chemotaxis; defense response to bacterium; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of GTPase activity; positive regulation of interleukin-1 alpha biosynthetic process; positive regulation of nitric-oxide synthase biosynthetic process; signal transduction; wound healing

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage