product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-NEFM/NF-M Antibody
catalog :
MBS421706
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, dog, cow
application :
western blot, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS421706
products type :
Antibody
products full name :
Goat anti-NEFM/NF-M Antibody
products short name :
NEFM/NF-M
products name syn :
NEFM; neurofilament, medium polypeptide; NEF3; NF-M; NFM; neurofilament triplet M protein; neurofilament, medium polypeptide 150kDa; neurofilament-3 (150 kD medium); NEFM antibody; neurofilament; medium polypeptide antibody; NEF3 antibody; NF-M antibody; NFM antibody; neurofilament triplet M protein antibody; neurofilament; medium polypeptide 150kDa antibody; neurofilament-3 (150 kD medium) antibody; NEFM / NF-M
other names :
neurofilament medium polypeptide isoform 1; Neurofilament medium polypeptide; neurofilament medium polypeptide; neurofilament, medium polypeptide; 160 kDa neurofilament protein; Neurofilament 3; Neurofilament triplet M protein
products gene name :
NEFM
products gene name syn :
NF-M
other gene names :
NEFM; NEFM; NFM; NEF3; NF-M; NEF3; NFM; NF-M
uniprot entry name :
NFM_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
sequence length :
916
sequence :
QASHITVERKDYLK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 170-200kDa band observed in Mouse Brain lysates (calculated MW of 102kDa according to NP_005373.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0. 03-0.1ug/ml.
other info1 :
Immunogen: Peptide with sequence C-QASHITVERKDYLK, from the internal region of the protein sequence according to NP_005373.2; NP_001099011.1. Epitope: Internal region
other info2 :
Note: This antibody is expected to recognize both reported isoforms (NP_005373.2; NP_001099011.1).
ncbi gi num :
157738649
ncbi acc num :
NP_005373.2
ncbi gb acc num :
NM_005382.2
ncbi mol weight :
59,468 Da
ncbi pathways :
Amyotrophic Lateral Sclerosis (ALS) Pathway (920975); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511)
ncbi summary :
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
uniprot summary :
NFM: a neurofilament intermediate filament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The levels of phosphorylation are altered developmentally and coincident with a change in the neurofilament function. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 8p21. Cellular Component: axon; neurofilament. Molecular Function: microtubule binding; protein binding; structural constituent of cytoskeleton. Biological Process: neurofilament bundle assembly
size1 :
0.1 mg
price1 :
300 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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