catalog number :
MBS421691
products full name :
Goat anti-HIVEP2/MIBP1 Antibody
products short name :
HIVEP2/MIBP1
products name syn :
HIVEP2; human immunodeficiency virus type I enhancer binding protein 2; HIV-EP2; MBP-2; MIBP1; SHN2; ZAS2; ZNF40B; MHC binding protein-2; OTTHUMP00000017321; OTTHUMP00000017322; OTTHUMP00000040180; Schnurri-2; c-myc intron binding protein 1; c-myc intron-; HIVEP2 antibody; human immunodeficiency virus type I enhancer binding protein 2 antibody; HIV-EP2 antibody; MBP-2 antibody; MIBP1 antibody; SHN2 antibody; ZAS2 antibody; ZNF40B antibody; MHC binding protein-2 antibody; OTTHUMP00000017321 antibody; OTTHUMP00000017322 antibody; OTTHUMP00000040180 antibody; Schnurri-2 antibody; c-myc intron binding protein 1 antibody; c-myc intron-binding protein 1 antibody; human immunodeficiency virus type I enhancer-binding protein 2 antibody
other names :
transcription factor HIVEP2; Transcription factor HIVEP2; transcription factor HIVEP2; human immunodeficiency virus type I enhancer binding protein 2; Human immunodeficiency virus type I enhancer-binding protein 2; HIV-EP2; MHC-binding protein 2; MBP-2
products gene name :
HIVEP2
products gene name syn :
MIBP1
other gene names :
HIVEP2; HIVEP2; SHN2; ZAS2; MBP-2; MIBP1; ZNF40B; HIV-EP2; HIV-EP2; MBP-2
uniprot entry name :
ZEP2_HUMAN
reactivity :
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Preliminary experiments in Human Lymph Node and Human Spleen lysates and in lysates of cell line MOLT4 gave no specific signal but low background (at antibody concentration up to 2ug/ml).
other info1 :
Immunogen: Peptide with sequence C-TEESKDPSSEKSQ, from the C Terminus of the protein sequence according to NP_006725.3. Epitope: C Terminus
ncbi acc num :
NP_006725.3
ncbi gb acc num :
NM_006734.3
ncbi mol weight :
269,053 Da
ncbi summary :
This gene encodes a member of a family of closely related, large, zinc finger-containing transcription factors. The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth, development and metastasis. The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs, a stretch of highly acidic amino acids and a serine/threonine-rich sequence. [provided by RefSeq, Nov 2012]
uniprot summary :
HIVEP2: This protein specifically binds to the DNA sequence 5'- GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon- beta genes. It may act in T-cell activation. Protein type: C2H2-type zinc finger protein; DNA-binding. Chromosomal Location of Human Ortholog: 6q23-q24. Cellular Component: nucleoplasm; nucleus. Molecular Function: DNA binding; metal ion binding; sequence-specific DNA binding; transcription factor activity. Biological Process: multicellular organismal development; regulation of transcription, DNA-dependent; signal transduction; transcription from RNA polymerase II promoter