catalog number :
MBS421671
products full name :
Goat anti-GATA3 Antibody
products short name :
GATA3
products name syn :
GATA3; GATA binding protein 3; HDR; MGC2346; MGC5199; MGC5445; GATA-binding protein 3; enhancer-binding protein GATA3; GATA3 antibody; GATA binding protein 3 antibody; HDR antibody; MGC2346 antibody; MGC5199 antibody; MGC5445 antibody; GATA-binding protein 3 antibody; enhancer-binding protein GATA3 antibody
other names :
trans-acting T-cell-specific transcription factor GATA-3 isoform 1; Trans-acting T-cell-specific transcription factor GATA-3; trans-acting T-cell-specific transcription factor GATA-3; GATA binding protein 3; GATA-binding factor 3
products gene name :
GATA3
other gene names :
GATA3; GATA3; HDR; HDRS
uniprot entry name :
GATA3_HUMAN
reactivity :
Tested: Human, Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 64000. Immunohistochemistry: In paraffin embedded Human Tonsil, stains nuclei of some cells in the interfollicular area and in germinal centres. Recommended concentration, 3ug/ml. Data obtained with a previous batch. Western Blot: Approx 46kDa band observed in Human Tonsil, Thymus, and Human Breast cancer lysates, and in Mouse Kidney lysates. (calculated MW of 47.9kDa according to NP_002042.1 and Mouse NP_032117.1). Recommended concentration: 0.3-1ug/ml.
other info1 :
Immunogen: Peptide with sequence EVTADQPRWVSHH-C, from the N Terminus of the protein sequence according to NP_001002295.1; NP_002042.1. Epitope: N Terminus
other info2 :
Note: This antibody is expected to recognize both reported isoforms (NP_001002295.1 and NP_002042.1).
ncbi acc num :
NP_001002295.1
ncbi gb acc num :
NM_001002295.1
ncbi mol weight :
48,045 Da
ncbi pathways :
Adipogenesis Pathway (198832); C-MYB Transcription Factor Network Pathway (138073); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (1269377); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hemostasis Pathway (1269340); IL27-mediated Signaling Events Pathway (137929); Inflammatory Bowel Disease (IBD) Pathway (842771); Inflammatory Bowel Disease (IBD) Pathway (842797); Notch Signaling Pathway (169345)
ncbi summary :
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009]