catalog number :
MBS421661
products full name :
Goat anti-SATB1 Antibody
products short name :
SATB1
products name syn :
SATB1; SATB homeobox 1; DNA-binding protein SATB1; special AT-rich sequence binding protein 1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA 1s); SATB1; SATB homeobox 1; DNA-binding protein SATB1; special AT-rich sequence binding protein 1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)
other names :
DNA-binding protein SATB1 isoform 1; DNA-binding protein SATB1; DNA-binding protein SATB1; special AT-rich sequence-binding protein 1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA); SATB homeobox 1; Special AT-rich sequence-binding protein 1
products gene name :
SATB1
other gene names :
SATB1; SATB1
uniprot entry name :
SATB1_HUMAN
reactivity :
Human, Mouse, Rat, Cow
sequence :
ESDEENRQKTRPRT
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Thymus shows select nuclear staining. Recommended concentration, 3-5ug/ml. Western Blot: Experiments gave bands at approx. 110kDa and 85kDa in lysates of cell line MOLT4 after 0.3ug/ml antibody staining. The observed 110kDa band corresponds to earlier findings in literature with different antibodies (De Belle et al, J Cell Biol. 1998 Apr 20;141(2):335-48.; PMID: 9548713). This protein has a calculated MW of 86.0kDa according to NP_002962.1. Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-ESDEENRQKTRPRT, from the internal region of the protein sequence according to NP_002962.1. Corresponding Immunizing Peptide: Catalog #MBS425023
other info2 :
Important Note: Reported variants NP_001124482.1 and NP_002962.1 represent identical protein.
ncbi acc num :
NP_002962.1
ncbi gb acc num :
NM_002971.4
ncbi mol weight :
89,127 Da
ncbi pathways :
Apoptosis Pathway 105648!!Apoptotic Cleavage Of Cellular Proteins Pathway 105678!!Apoptotic Execution Phase Pathway 105677!!Caspase Cascade In Apoptosis Pathway 137974
ncbi summary :
This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]