catalog number :
MBS421650
products full name :
Goat anti-Neurotrophin 5 / NT4 Antibody
products short name :
Neurotrophin 5/NT4
products name syn :
NT4; neurotrophin 5 (neurotrophin 4/5); NTF5; NT-4/5; NT5; NTF4; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 4; neurotrophin 5; NT4; neurotrophin 5 (neurotrophin 4/5); NTF5; NT-4/5; NT5; NTF4; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 4; neurotrophin 5
other names :
neurotrophin-4 preproprotein; Neurotrophin-4; neurotrophin-4; neurotrophin-5; neutrophic factor 4; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 5 (neurotrophin 4/5); neurotrophin 4; Neurotrophin-5; NT-5; Neutrophic factor 4
products gene name :
NTF5
other gene names :
NTF4; NTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5; NTF5; NT-4; NT-5
uniprot entry name :
NTF4_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 55kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 22.4kDa according to NP_006170.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Ghinelli et al, Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3352-7; PMID: 12882781). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence FETRCKADNAEEG, from the internal region of the protein sequence according to NP_006170.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426945
ncbi acc num :
NP_006170.1
ncbi gb acc num :
NM_006179.4
ncbi mol weight :
22,427 Da
ncbi pathways :
MAPK Signaling Pathway 198779!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Neurotrophic Factor-mediated Trk Receptor Signaling Pathway 137977!!Neurotrophin Signaling Pathway 101143!!Neurotrophin Signaling Pathway 100064!!P75(NTR)-mediated Signaling Pathway 138019
ncbi summary :
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008]