product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-E2F8 Antibody
catalog :
MBS421643
quantity :
0.1 mg
price :
225 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421643
products type :
Antibody
products full name :
Goat anti-E2F8 Antibody
products short name :
E2F8
products name syn :
E2F8; E2F transcription factor 8; FLJ23311; E2F family member 8; E2F8 antibody; E2F transcription factor 8 antibody; FLJ23311 antibody; E2F family member 8 antibody
other names :
transcription factor E2F8; Transcription factor E2F8; transcription factor E2F8; E2F transcription factor 8
products gene name :
E2F8
other gene names :
E2F8; E2F8; E2F-8; E2F-8
uniprot entry name :
E2F8_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Expected from sequence similarity: Human, Mouse
sequence length :
867
sequence :
KSIESDRRKINSAPS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Preliminary experiments in Human Thymus lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
other info1 :
Immunogen: Peptide with sequence C-KSIESDRRKINSAPS, from the internal region of the protein sequence according to NP_078956.2. Epitope: Internal region
ncbi gi num :
38505226
ncbi acc num :
NP_078956.2
ncbi gb acc num :
NM_024680.3
ncbi mol weight :
94,166 Da
ncbi summary :
This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012]
uniprot summary :
E2F8: Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Belongs to the E2F/DP family. Protein type: DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 11p15.1. Cellular Component: nucleus; transcription factor complex. Molecular Function: protein binding; protein homodimerization activity; transcription corepressor activity; transcription factor activity. Biological Process: cell cycle comprising mitosis without cytokinesis; cell proliferation; negative regulation of cytokinesis; negative regulation of transcription from RNA polymerase II promoter; placenta development; positive regulation of DNA endoreduplication; positive regulation of transcription from RNA polymerase II promoter; sprouting angiogenesis; transcription, DNA-dependent
size1 :
0.1 mg
price1 :
225 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!