catalog number :
MBS421631
products full name :
Goat anti-SAR1 Antibody
products short name :
SAR1
products name syn :
SAR1A; SAR1 gene homolog A (S. cerevisiae); SAR1; SARA1; Sara; masra2; OTTHUMP00000060603; SAR1a gene homolog 1; SAR1A antibody; SAR1 gene homolog A (S. cerevisiae) antibody; SAR1 antibody; SARA1 antibody; Sara antibody; masra2 antibody; OTTHUMP00000060603 antibody; SAR1a gene homolog 1 antibody
other names :
GTP-binding protein SAR1a; GTP-binding protein SAR1a; GTP-binding protein SAR1a; secretion associated Ras related GTPase 1A; COPII-associated small GTPase
products gene name :
SAR1A
products gene name syn :
SAR1
other gene names :
SAR1A; SAR1A; SAR1; Sara; SARA1; masra2; SAR1; SARA; SARA1
uniprot entry name :
SAR1A_HUMAN
reactivity :
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx.23 kDa band observed in lysates of NIH3T3 (calculated MW of 22.4 kDa according to Human NP_064535.1 and to Mouse NP_033146.1). Recommended concentration: 0.1-0.3ug/ml.
other info1 :
Immunogen: Peptide with sequence C-HSRLVESKVELNA, from the internal region of the protein sequence according to NP_064535.1. Epitope: Internal region
ncbi acc num :
NP_064535.1
ncbi gb acc num :
NM_020150.4
ncbi mol weight :
17,500 Da
ncbi pathways :
COPII Complex Pathway (413469); COPII Complex Pathway (890619); Legionellosis Pathway (469200); Legionellosis Pathway (469186); Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190); SREBP Signalling Pathway (219802)
uniprot summary :
SAR1A: Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). Belongs to the small GTPase superfamily. SAR1 family. Protein type: G protein; G protein, monomeric; G protein, monomeric, SAR1. Chromosomal Location of Human Ortholog: 10q22.1. Cellular Component: endoplasmic reticulum; Golgi apparatus. Molecular Function: GTP binding. Biological Process: intracellular protein transport; small GTPase mediated signal transduction; vesicle-mediated transport