catalog number :
MBS421607
products full name :
Goat anti-TUSC3 / N33 Antibody
products short name :
TUSC3/N33
products name syn :
TUSC3; tumor suppressor candidate 3; D8S1992; MGC13453; N33; OST3A; Putative prostate cancer tumor suppressor; TUSC3; tumor suppressor candidate 3; D8S1992; MGC13453; N33; OST3A; Putative prostate cancer tumor suppressor
other names :
tumor suppressor candidate 3 isoform a; Tumor suppressor candidate 3; tumor suppressor candidate 3; magnesium uptake/transporter TUSC3; oligosaccharyltransferase 3 homolog A; Putative prostate cancer tumor suppressor; tumor suppressor candidate 3; Magnesium uptake/transporter TUSC3; Protein N33
products gene name :
TUSC3
other gene names :
TUSC3; TUSC3; M33; N33; MRT7; MRT22; OST3A; D8S1992; N33
uniprot entry name :
TUSC3_HUMAN
reactivity :
Human, Mouse, Rat, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 37kDa band observed in Human Liver lysates (calculated MW of 39.7kDa according to NP_006756.2 and of 39.6kDa according to NP_839952.1). Recommended concentration: 1-3ug/ml.
An additional band of unknown identity was also consistently observed at 22kDa. This band was successfully blocked by incubation with the immunising peptide. Peptide ELISA: antibody detection limit dilution 1:1000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence PQRQCSVCRQAN, from the internal region of the protein sequence according to NP_006756.2; NP_839952.1. Corresponding Immunizing Peptide: Catalog #MBS425516
other info2 :
Important Note: This antibody is expected to recognise both reported isoforms (NP_006756.2; NP_839952.1).
ncbi acc num :
NP_006756.2
ncbi gb acc num :
NM_006765.3
ncbi mol weight :
39,558 Da
ncbi pathways :
Asparagine N-linked Glycosylation Pathway 161013!!Metabolic Pathways 132956!!Metabolism Of Proteins Pathway 106230!!N-Glycan Biosynthesis Pathway 82975!!N-Glycan Biosynthesis Pathway 345!!N-glycosylation By Oligosaccharyltransferase Pathway 413373!!N-glycosylation By Oligosaccharyltransferase Pathway 890439!!Post-translational Protein Modification Pathway 161012!!Protein Processing In Endoplasmic Reticulum Pathway 167325!!Protein Processing In Endoplasmic Reticulum Pathway 167190
ncbi summary :
This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]