antibody

Goat anti-BDH2/DHRS6 (aa 60 to 71) Antibody

MBS421578

0.1 mg

300 USD

polyclonal

goat

nonconjugated

human, mouse, rat

western blot, enzyme immunoassay

Antibody

Goat anti-BDH2/DHRS6 (aa 60 to 71) Antibody

BDH2/DHRS6

Goat Anti-BDH2 / DHRS6 (aa 92 to 103) Antibody; BDH2; DHRS6; 3-hydroxybutyrate dehydrogenase, type 2; EFA6R; FLJ13261; PRO20933; UCPA-OR; UNQ6308; dehydrogenase/reductase (SDR family) member 6; oxidoreductase UCPA; BDH2 antibody; DHRS6 antibody; 3-hydroxybutyrate dehydrogenase; type 2 antibody; EFA6R antibody; FLJ13261 antibody; PRO20933 antibody; UCPA-OR antibody; UNQ6308 antibody; dehydrogenase/reductase (SDR family) member 6 antibody; oxidoreductase UCPA antibody; BDH2 / DHRS6 (aa 60 to 71)

3-hydroxybutyrate dehydrogenase type 2; 3-hydroxybutyrate dehydrogenase type 2; 3-hydroxybutyrate dehydrogenase type 2; 3-hydroxybutyrate dehydrogenase, type 2; Dehydrogenase/reductase SDR family member 6; Oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; Short chain dehydrogenase/reductase family 15C member 1

BDH2

DHRS6

BDH2; BDH2; DHRS6; EFA6R; SDR15C1; UCPA-OR; UNQ6308; PRO20933; DHRS6; SDR15C1

BDH2_HUMAN

Polyclonal

Goat

Tested: Human; Expected from sequence similarity: Human, Mouse, Rat

245

TKKKQIDQFANE

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Approx 26kDa band observed in Human Brain (Cerebellum), Kidney and Liver lysates (calculated MW of 26.7kDa according to NP_064524.3). In transfected HEK293 transiently expressing BDH2 a band of approx.29kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.3-1ug/ml.

Immunogen: Peptide with sequence C-TKKKQIDQFANE, from the internal region of the protein sequence according to NP_064524.3. Epitope: Internal region

66933014

NP_064524.3

NM_020139.3

15,626 Da

Butanoate Metabolism Pathway (83007); Butanoate Metabolism Pathway (391); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (1270010); Ketone Body Metabolism Pathway (1270026); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Synthesis And Degradation Of Ketone Bodies Pathway (82936); Synthesis And Degradation Of Ketone Bodies Pathway (297); Synthesis Of Ketone Bodies Pathway (1270027)

DHRS6: Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.1.1.30; Oxidoreductase; Lipid Metabolism - synthesis and degradation of ketone bodies; Carbohydrate Metabolism - butanoate. Chromosomal Location of Human Ortholog: 4q24. Cellular Component: cytoplasm; cytosol; mitochondrion. Molecular Function: 3-hydroxybutyrate dehydrogenase activity; NAD binding; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Biological Process: epithelial cell differentiation; fatty acid beta-oxidation; heme metabolic process; iron ion homeostasis; ketone body biosynthetic process; siderophore biosynthetic process

0.1 mg

300 USD