product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-MP100/NPEPPS Antibody
catalog :
MBS421564
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421564
products type :
Antibody
products full name :
Goat anti-MP100/NPEPPS Antibody
products short name :
MP100/NPEPPS
products name syn :
NPEPPS; MP100; aminopeptidase puromycin sensitive; PSA; metalloproteinase MP100; puromycin-sensitive aminopeptidase; NPEPPS antibody; MP100 antibody; aminopeptidase puromycin sensitive antibody; PSA antibody; metalloproteinase MP100 antibody; puromycin-sensitive aminopeptidase antibody
other names :
aminopeptidase puromycin sensitive; Puromycin-sensitive aminopeptidase; puromycin-sensitive aminopeptidase; aminopeptidase puromycin sensitive; Cytosol alanyl aminopeptidase; AAP-S
products gene name :
NPEPPS
products gene name syn :
MP100
other gene names :
NPEPPS; NPEPPS; PSA; AAP-S; MP100; PSA; PSA; AAP-S
uniprot entry name :
PSA_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat
sequence length :
875
sequence :
KRDAESIHQYLLQRK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 4000. Western Blot: Approx 110kDa band observed in Human Brain (Cerebral Cortex) lysates (calculated MW of 98.5kDa according to NP_006301.2). Recommended concentration: 0.2-0.5ug/ml.
other info1 :
Immunogen: Peptide with sequence C-KRDAESIHQYLLQRK, from the internal region of the protein sequence according to NP_006301.2. Epitope: Internal region
ncbi gi num :
15451907
ncbi acc num :
NP_006301.2
ncbi gb acc num :
NM_006310.2
ncbi mol weight :
94,516 Da
ncbi pathways :
Adaptive Immune System Pathway (1269171); Antigen Processing: Ubiquitination Proteasome Degradation Pathway (1269193); Class I MHC Mediated Antigen Processing Presentation Pathway (1269192); Immune System Pathway (1269170)
ncbi summary :
This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]
uniprot summary :
NPEPPS: Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. Belongs to the peptidase M1 family. Protein type: Protease; EC 3.4.11.14. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: cytosol; nucleus; plasma membrane. Molecular Function: aminopeptidase activity; peptide binding; zinc ion binding. Biological Process: peptide catabolic process; protein polyubiquitination; proteolysis
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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