catalog number :
MBS421554
products full name :
Goat anti-CRHR1 / CRF-R (aa 107 - 117) Antibody
products short name :
CRHR1/CRF-R
products name syn :
CRHR1; CRF-R; corticotropin releasing hormone receptor 1; CRF1; CRFR1; CRH-R1h; CRHR; CRHR1f; corticotropin releasing hormone receptor variant 1h; seven transmembrane helix receptor; Goat Anti-CRHR1 / CRF-R (aa 250 - 263); CRHR1; CRF-R; corticotropin releasing hormone receptor 1; CRF1; CRFR1; CRH-R1h; CRHR; CRHR1f; corticotropin releasing hormone receptor variant 1h; seven transmembrane helix receptor
other names :
corticotropin-releasing factor receptor 1 isoform 2; Corticotropin-releasing factor receptor 1; corticotropin-releasing factor receptor 1; CRH receptor 1; seven transmembrane helix receptor; corticotropin-releasing factor type 1 receptor; corticotropin releasing hormone receptor 1; Corticotropin-releasing hormone receptor 1; CRH-R-1; CRH-R1
products gene name :
CRHR1
other gene names :
CRHR1; CRHR1; CRF1; CRHR; CRF-R; CRFR1; CRF-R1; CRFR-1; CRH-R1; CRHR1L; CRF-R-1; CRH-R-1; CRFR; CRFR1; CRHR; CRF-R-1; CRF-R1; CRFR-1; CRH-R-1; CRH-R1
uniprot entry name :
CRFR1_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-NEEKKSKVHYH, from the internal region of the protein sequence according to NP_004373.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426154
ncbi acc num :
NP_004373.2
ncbi gb acc num :
NM_004382.4
ncbi mol weight :
28,122 Da
ncbi pathways :
Class B/2 (Secretin Family Receptors) Pathway 106378!!Corticotropin-releasing Hormone Pathway 920957!!G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class B Secretin-like Pathway 198781!!Long-term Depression Pathway 83086!!Long-term Depression Pathway 497!!Myometrial Relaxation And Contraction Pathways 198759!!Neuroactive Ligand-receptor Interaction Pathway 83053
ncbi summary :
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Readthrough transcription also exists between this gene and upstream GeneID:401884 (ADP-ribosylation factor 3 pseudogene), and the readthrough transcripts encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Dec 2014]