Goat anti-AVPR1A Antibody | MyBioSource MBS421528 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-AVPR1A Antibody

catalog :

MBS421528

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS421528

products type :

Antibody

products full name :

Goat anti-AVPR1A Antibody

products short name :

AVPR1A

products name syn :

AVPR1A; arginine vasopressin receptor 1A; AVPR1; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; V1a vasopressin receptor; antidiuretic hormone receptor 1A; vascular/hepatic-type arginine vasopressin receptor; AVPR1A antibody; arginine vasopressin receptor 1A antibody; AVPR1 antibody; SCCL vasopressin subtype 1a receptor antibody; V1-vascular vasopressin receptor AVPR1A antibody; V1a vasopressin receptor antibody; antidiuretic hormone receptor 1A antibody; vascular/hepatic-type arginine vasopressin receptor antibody

other names :

vasopressin V1a receptor; Vasopressin V1a receptor; vasopressin V1a receptor; arginine vasopressin receptor 1A; AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor

products gene name :

AVPR1A

other gene names :

AVPR1A; AVPR1A; V1aR; AVPR1; AVPR V1a; AVPR1; V1aR

uniprot entry name :

V1AR_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow

sequence length :

418

sequence :

CHPLKTLQQPARRSR

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Approx 85kDa band observed in Human Brain (Frontal cortex) lysates and in Rat Brain lysates and in lysates of cell line NIH3T3 (calculated MW of 46.8kDa according to NP_000697.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Phalipou et al, J Biol Chem.1997 Oct 17;272(42): 26536-44; PMID: 9334232). Recommended concentration: 0. 03-0.1ug/ml.

other info1 :

Immunogen: Peptide with sequence CHPLKTLQQPARRSR, from the internal region of the protein sequence according to NP_000697.1. Epitope: Internal region

ncbi gi num :

4502331

ncbi acc num :

NP_000697.1

ncbi gb acc num :

NM_000706.4

ncbi mol weight :

46,800 Da

ncbi pathways :

Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Defective AVP Causes Neurohypophyseal Diabetes Insipidus (NDI) Pathway (1309124); Disease Pathway (1268854); Disorders Of Transmembrane Transporters Pathway (1268932); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886)

ncbi summary :

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]

uniprot summary :

AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR. Chromosomal Location of Human Ortholog: 12q14-q15. Cellular Component: cytoplasmic vesicle; cytosol; endosome; integral to plasma membrane; plasma membrane. Molecular Function: peptide binding; peptide hormone binding; protein binding; protein kinase C binding; V1A vasopressin receptor binding; vasopressin receptor activity. Biological Process: blood circulation; calcium-mediated signaling; cellular response to hormone stimulus; cellular response to water deprivation; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; generation of precursor metabolites and energy; grooming behavior; maternal behavior; myotube differentiation; negative regulation of female receptivity; negative regulation of transmission of nerve impulse; penile erection; phospholipase C activation; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; positive regulation of heart rate; positive regulation of prostaglandin biosynthetic process; positive regulation of systemic arterial blood pressure; positive regulation of vasoconstriction; regulation of systemic arterial blood pressure by vasopressin; response to corticosterone stimulus; social behavior; sperm ejaculation; telencephalon development

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage