catalog number :
MBS421513
products full name :
Goat anti-TRPM7 / LTRPC7 Antibody
products short name :
TRPM7/LTRPC7
products name syn :
TRPM7; transient receptor potential cation channel; subfamily M; member 7; CHAK; CHAK1; LTRPC7; FLJ20117; TRP-PLIK; LTRPC ion channel family member 7; homolog of mouse transient receptor potential-phospholipase C-interacting kinase CHaK hypothetical protein FLJ20117; FLJ25718; TRPM7; transient receptor potential cation channel, subfamily M, member 7; CHAK; CHAK1; LTRPC7; FLJ20117; TRP-PLIK; LTRPC ion channel family member 7; homolog of mouse transient receptor potential-phospholipase C-interacting kinase CHaK hypothetical protein FLJ20117; FLJ25718
other names :
transient receptor potential cation channel subfamily M member 7 isoform a; Transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel subfamily M member 7; channel-kinase 1; LTRPC ion channel family member 7; long transient receptor potential channel 7; transient receptor potential-phospholipase C-interacting kinase; transient receptor potential cation channel, subfamily M, member 7; Channel-kinase 1; Long transient receptor potential channel 7; LTrpC-7; LTrpC7
products gene name :
TRPM7
other gene names :
TRPM7; TRPM7; CHAK; CHAK1; ALSPDC; LTRPC7; LTrpC-7; TRP-PLIK; CHAK1; LTRPC7; LTrpC-7; LTrpC7
uniprot entry name :
TRPM7_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Crayfish
sequence :
TKESESTNSVRLML
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Mouse Brain shows neuronal staining in the hippocampus. Recommended concentration, 4-6ug/ml.
This antibody has been successfully used in IHC for rat hippocampus. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-TKESESTNSVRLML, from the C Terminus of the protein sequence according to NP_060142.3.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425263
ncbi acc num :
NP_060142.3
ncbi gb acc num :
NM_017672.5
ncbi mol weight :
212,697 Da
ncbi pathways :
Ion Channel Transport Pathway 187193!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220!!Stimuli-sensing Channels Pathway 771568!!TRP Channels Pathway 906028!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014]