catalog number :
MBS421492
products full name :
Goat anti-ARP2/3 subunit 1B Antibody
products short name :
ARP2/3 subunit 1B
products name syn :
ARPC1B; actin related protein 2/3 complex; subunit 1B; 41kDa; ARC41; p40-ARC; p41-ARC; ARP2/3 protein complex subunit p41; actin related protein 2/3 complex; subunit 1A (41 kD); OTTHUMP00000206020; actin related protein 2/3 complex, subunit 1B, 41kDa; ARC41; p40-ARC; p41-ARC; ARP2/3 protein complex subunit p41; actin related protein 2/3 complex, subunit 1A (41 kD); OTTHUMP00000206020
other names :
actin-related protein 2/3 complex subunit 1B; Actin-related protein 2/3 complex subunit 1B; actin-related protein 2/3 complex subunit 1B; arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41; actin related protein 2/3 complex, subunit 1B, 41kDa; Arp2/3 complex 41 kDa subunit; p41-ARC
products gene name :
ARPC1B
other gene names :
ARPC1B; ARPC1B; ARC41; p40-ARC; p41-ARC; ARC41
uniprot entry name :
ARC1B_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 37kDa band observed in Human Liver lysates (calculated MW of 40.9kDa according to NP_005711). Recommended concentration: 2-4ug/ml. A minor band of unknown identity was also consistently observed at 28kDa. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence AYHSFLVEPISCH, from the N Terminus of the protein sequence according to NP_005711.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425253
ncbi acc num :
NP_005711.1
ncbi gb acc num :
NM_005720.3
ncbi mol weight :
40,950 Da
ncbi pathways :
B Cell Receptor Signaling Pathway 198909!!Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!CDC42 Signaling Events Pathway 137994!!ErbB1 Downstream Signaling Pathway 138057!!Fc Gamma R-mediated Phagocytosis Pathway 114228!!Fc Gamma R-mediated Phagocytosis Pathway 106590!!Pathogenic Escherichia Coli Infection Pathway 83103!!Pathogenic Escherichia Coli Infection Pathway 672459!!Pathogenic Escherichia Coli Infection Pathway 516
ncbi summary :
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011]