catalog number :
MBS421477
products full name :
Goat anti-Arginase, type 1/arg1(rat) Antibody
products short name :
Arginase, type 1/arg1
products name syn :
Arg1; arginase 1; AI type I arginase; arginase 1 liver; Arg1 antibody; arginase 1 antibody; AI type I arginase antibody; arginase 1 liver antibody; Arginase, type 1; Arginase, type 1 / arg1(rat)
other names :
arginase-1; Arginase-1; arginase-1; arginase 1; Liver-type arginase; Type I arginase
products gene name :
Arg1
products gene name syn :
ARG1
other gene names :
Arg1; Arg1
uniprot entry name :
ARGI1_RAT
reactivity :
Tested: Mouse, Rat; Expected from sequence similarity: Mouse, Rat
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Approx 37kDa band observed in Mouse and Rat Liver lysates (calculated MW of 34.8kDa according to mouse NP_031508.1). Recommended concentration: 1-3ug/ml.
other info1 :
Immunogen: Peptide with sequence C-NHKPETDYLKPPK, from the C Terminus of the protein sequence according to NP_058830.2. Epitope: C Terminus
ncbi acc num :
NP_058830.2
ncbi gb acc num :
NM_017134.3
ncbi mol weight :
34,973 Da
ncbi pathways :
Amoebiasis Pathway (167311); Amoebiasis Pathway (167191); Arginine And Proline Metabolism Pathway (83349); Arginine And Proline Metabolism Pathway (323); Arginine Biosynthesis Pathway (83336); Arginine Biosynthesis Pathway (306); Biosynthesis Of Amino Acids Pathway (791250); Biosynthesis Of Amino Acids Pathway (795174); Metabolic Pathways (132933); Metabolism Pathway (1377550)
ncbi summary :
catalyzes the hydrolysis of arginine to ornithine and urea in arginine metabolism; regulates nitric oxide production [RGD, Feb 2006]
uniprot summary :
ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.5.3.1; Amino Acid Metabolism - arginine and proline; Hydrolase. Cellular Component: cell soma; cytoplasm; extracellular space; mitochondrial outer membrane; neuron projection; nucleus. Molecular Function: arginase activity; manganese ion binding. Biological Process: aging; arginine catabolic process to ornithine; arginine metabolic process; collagen biosynthetic process; female pregnancy; liver development; lung development; mammary gland involution; maternal process involved in pregnancy; positive regulation of endothelial cell proliferation; response to amine stimulus; response to amino acid stimulus; response to axon injury; response to cadmium ion; response to drug; response to herbicide; response to lipopolysaccharide; response to manganese ion; response to methylmercury; response to peptide hormone stimulus; response to selenium ion; response to steroid hormone stimulus; response to vitamin A; response to vitamin E; response to wounding; response to zinc ion; urea cycle