catalog number :
MBS421470
products full name :
Goat anti-GALR1 (internal) Antibody
products short name :
GALR1
products name syn :
GALR1; galanin receptor 1; GALNR; GALNR1; Goat Anti-GALR1 (C Term); GALR1; galanin receptor 1; GALNR; GALNR1
other names :
galanin receptor type 1; Galanin receptor type 1; galanin receptor type 1; GAL1-R; GALR-1; galanin receptor 1
products gene name :
GALR1
other gene names :
GALR1; GALR1; GALNR; GALNR1; GALNR; GALNR1; GAL1-R; GALR-1
uniprot entry name :
GALR1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 24-25kDa and 37kDa bands observed in lysates of Rat Spinal Cord (calculated MW of 24.9kDa according to Rat NP_037090.1 and calculated MW of 38.9kDa according to AAC52438.1 and sp Q62805). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-RSKPGKPRSTTN, from the internal region of the protein sequence according to NP_001471.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425090
ncbi acc num :
NP_001471.2
ncbi gb acc num :
NM_001480.3
ncbi mol weight :
38,953 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (i) Signalling Events Pathway 119550!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462!!Peptide GPCRs Pathway 198897!!Peptide Ligand-binding Receptors Pathway 106358!!Signal Transduction Pathway 477114
ncbi summary :
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]