catalog number :
MBS421461
products full name :
Goat anti-EGR2 Antibody
products short name :
EGR2
products name syn :
EGR2; early growth response 2 (Krox-20 homolog; Drosophila); CMT1D; CMT4E; DKFZp686J1957; FLJ14547; KROX20; KROX-20; Drosophila; homolog (early growth response-2); Krox-20 homolog; OTTHUMP00000062133; early growth response 2 protein; EGR2; early growth response 2 (Krox-20 homolog, Drosophila); CMT1D; CMT4E; DKFZp686J1957; FLJ14547; KROX20; KROX-20, Drosophila, homolog (early growth response-2); Krox-20 homolog; OTTHUMP00000062133; early growth response 2 protein
other names :
E3 SUMO-protein ligase EGR2 isoform a; E3 SUMO-protein ligase EGR2; E3 SUMO-protein ligase EGR2; zinc finger protein Krox-20; early growth response protein 2; KROX-20, Drosophila, homolog (early growth response-2); early growth response 2; AT591; Early growth response protein 2; EGR-2; Zinc finger protein Krox-20
products gene name :
EGR2
other gene names :
EGR2; EGR2; AT591; CMT1D; CMT4E; KROX20; KROX20; EGR-2
uniprot entry name :
EGR2_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Colon shows nuclear staining of absorptive cells. Recommended concentration, 3-5ug/ml. Western Blot: Approx 55kDa band observed in lysates of cell line HepG2 (calculated MW of 50.3kDa according to NP_000390.2). Recommended concentration: 0.03-0.1ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence HGTAGPDRKPFPC, from the internal region of the protein sequence according to NP_000390.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426237
ncbi acc num :
NP_000390.2
ncbi gb acc num :
NM_000399.3
ncbi mol weight :
44,970 Da
ncbi pathways :
Adipogenesis Pathway 198832!!BDNF Signaling Pathway 712093!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Developmental Biology Pathway 477129!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Hepatitis B Pathway 694606!!IL4-mediated Signaling Events Pathway 137933!!Transcriptional Regulation Of White Adipocyte Differentiation Pathway 205243!!Viral Carcinogenesis Pathway 658418
ncbi summary :
The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]