catalog number :
MBS421438
products full name :
Goat anti-GST3 / GSTP1 Antibody
products short name :
GST3/GSTP1
products name syn :
GSTP1; GST3; glutathione S-transferase pi; HGNC:4638; DFN7; FAEES3; PI; deafness; X-linked 7; fatty acid ethyl ester synthase III; glutathione transferase; glutathione S-transferase pi 1; GSTP1; GST3; glutathione S-transferase pi; HGNC:4638; DFN7; FAEES3; PI; deafness, X-linked 7; fatty acid ethyl ester synthase III; glutathione transferase; glutathione S-transferase pi 1
other names :
glutathione S-transferase P; Glutathione S-transferase P; glutathione S-transferase P; GSTP1-1; GST class-pi; deafness, X-linked 7; epididymis secretory protein Li 22; fatty acid ethyl ester synthase III; glutathione S-transferase pi 1; GST class-pi; GSTP1-1
products gene name :
GSTP1
other gene names :
GSTP1; GSTP1; PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22; FAEES3; GST3
uniprot entry name :
GSTP1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 24kDa band observed in Human Kidney, Liver and Lung lysates (calculated MW of 23.4kDa according to NP_000843.1). In transfected HEK293 transiently expressing GSTP1 band of approx. 26 kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.01-0.03ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-LADQGQSWKEEV, from the internal region of the protein sequence according to NP_000843.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426661
ncbi acc num :
NP_000843.1
ncbi gb acc num :
NM_000852.3
ncbi mol weight :
23,356 Da
ncbi pathways :
4-hydroxy-2-nonenal Detoxification Pathway 703096!!Arachidonate Epoxygenase / Epoxide Hydrolase Pathway 198838!!Biological Oxidations Pathway 105698!!Cellular Responses To Stress Pathway 645258!!Chemical Carcinogenesis Pathway 673221!!Chemical Carcinogenesis Pathway 673237!!Detoxification Of Reactive Oxygen Species Pathway 941400!!Diurnally Regulated Genes With Circadian Orthologs Pathway 198813!!Drug Metabolism - Cytochrome P450 Pathway 83032!!Drug Metabolism - Cytochrome P450 Pathway 427
ncbi summary :
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]