product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-P27KIP1 / CDKN1B (C Terminus) Antibody
catalog :
MBS421409
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS421409
products type :
Antibody
products full name :
Goat anti-P27KIP1 / CDKN1B (C Terminus) Antibody
products short name :
P27KIP1/CDKN1B
products name syn :
CDKN1B; P27KIP1; cyclin-dependent kinase inhibitor 1B (p27; Kip1); KIP1; CDKN4; cyclin-dependent kinase inhibitor 1B; p27(KIP1); KIP1; p27; MEN1B; MEN4; P27KIP1; Goat Anti-KIP1 / CDKN1B (internal); CDKN1B; P27KIP1; cyclin-dependent kinase inhibitor 1B (p27, Kip1); KIP1; CDKN4; cyclin-dependent kinase inhibitor 1B; p27(KIP1); KIP1; p27; MEN1B; MEN4; P27KIP1
other names :
cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B (p27, Kip1); Cyclin-dependent kinase inhibitor p27; p27Kip1
products gene name :
CDKN1B
other gene names :
CDKN1B; CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1; KIP1
uniprot entry name :
CDN1B_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Cow, Dog
sequence length :
198
sequence :
EQTPKKPGLRRRQT
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP)
app notes :
Western Blot: Approx 26-27kDa band observed in Human Breast and Prostate lysates (calculated MW of 22.1kDa according to NP_004055.1). The observed molecular weight corresponds to earlier findings in literature (Xia et al, Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):14028-33; PMID: 16169901). Recommended concentration: 0.5-1.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000. Immunoprecipitation:This antibody was deemed fit for IP under native conditions (observations from anonymous customer).
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-EQTPKKPGLRRRQT, from the C Terminus of the protein sequence according to NP_004055.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428575
ncbi gi num :
4757962
ncbi acc num :
NP_004055.1
ncbi gb acc num :
NM_004064.4
ncbi mol weight :
22,073 Da
ncbi pathways :
AKT Phosphorylates Targets In The Cytosol Pathway 106475!!Adaptive Immune System Pathway 366160!!AhR Pathway 755436!!C-MYB Transcription Factor Network Pathway 138073!!Cell Cycle Pathway 530733!!Cell Cycle Checkpoints Pathway 105739!!Cell Cycle, Mitotic Pathway 105765!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054!!Cell Cycle Pathway 463
ncbi summary :
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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