catalog number :
MBS421407
products full name :
Goat anti-ARMET Antibody
products short name :
ARMET
products name syn :
ARMET; arginine-rich; mutated in early stage tumors; ARP; MANF; MGC142148; MGC142150; arginine-rich protein; arginine-rich, mutated in early stage tumors; ARP; MANF; MGC142148; MGC142150; arginine-rich protein
other names :
mesencephalic astrocyte-derived neurotrophic factor; Mesencephalic astrocyte-derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; arginine-rich, mutated in early stage tumors; mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET
products gene name :
ARMET
other gene names :
MANF; MANF; ARP; ARMET; ARMET; ARP
uniprot entry name :
MANF_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 21kDa band observed in Human Pancreas lysates (calculated MW of 21.1kDa according to NP_006001.2). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence KFCREARGKENR, from the internal region of the protein sequence according to NP_006001.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426908
ncbi acc num :
NP_006001.2
ncbi gb acc num :
NM_006010.3
ncbi mol weight :
20,700 Da
ncbi summary :
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014]