product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Neurochondrin Antibody
catalog :
MBS421400
quantity :
0.1 mg
price :
225 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421400
products type :
Antibody
products full name :
Goat anti-Neurochondrin Antibody
products short name :
Neurochondrin
products name syn :
NCDN; neurochondrin; KIAA0607; NCDN antibody; neurochondrin antibody; KIAA0607 antibody; Neurochondrin; Neurochondrin
other names :
neurochondrin isoform 1; Neurochondrin; neurochondrin; neurochondrin
products gene name :
NCDN
other gene names :
NCDN; NCDN; KIAA0607
uniprot entry name :
NCDN_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
sequence length :
729
sequence :
HYLLQVGSEKQKEP
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Preliminary experiments gave bands at approx 100kDa and140kDa in Human Brain (Cerebellum) lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 78.9kDa according to NP_055099.1 and 77.2kDa according to NP_001014841.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
other info1 :
Immunogen: Peptide with sequence C-HYLLQVGSEKQKEP, from the internal region of the protein sequence according to NP_055099.1; NP_001014841.1. Epitope: Internal region
other info2 :
Note: This antibody is expected to recognize both reported isoforms (NP_055099.1; NP_001014841.1). Reported variants represent identical protein (NP_055099.1; NP_001014839.1).
ncbi gi num :
24307949
ncbi acc num :
NP_055099.1
ncbi gb acc num :
NM_014284.2
ncbi mol weight :
79,158 Da
ncbi summary :
This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2008]
uniprot summary :
NCDN: Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth. Belongs to the neurochondrin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Inhibitor. Chromosomal Location of Human Ortholog: 1p34.3. Cellular Component: axon; cell soma; cytosol; dendrite; membrane; nucleus. Molecular Function: protein binding. Biological Process: bone resorption; neurite development; regulation of neuronal synaptic plasticity
size1 :
0.1 mg
price1 :
225 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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