catalog number :
MBS421397
products full name :
Goat anti-TSPO / PBR (isoform) Antibody
products short name :
TSPO/PBR
products name syn :
TSPO; PBR; translocator protein (18kDa); BZRP; DBI; IBP; MBR; PKBS; PTBR; mDRC; pk18; OTTHUMP00000028891; benzodiazapine receptor (peripheral); benzodiazepine peripheral binding site; mitochondrial benzodiazepine receptor; peripheral benzodiazepine receptor; peripheral-type benzodiazepine receptor; TSPO; PBR; translocator protein (18kDa); BZRP; DBI; IBP; MBR; PKBS; PTBR; mDRC; pk18; OTTHUMP00000028891; benzodiazapine receptor (peripheral); benzodiazepine peripheral binding site; mitochondrial benzodiazepine receptor; peripheral benzodiazepine receptor; peripheral-type benzodiazepine receptor
other names :
translocator protein; Translocator protein; translocator protein; mitochondrial benzodiazepine receptor; benzodiazepine peripheral binding site; peripheral-type benzodiazepine receptor; translocator protein (18kDa); Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR
products gene name :
TSPO
other gene names :
TSPO; TSPO; DBI; IBP; MBR; PBR; PBS; BPBS; BZRP; PKBS; PTBR; mDRC; pk18; BZRP; MBR; PBR
uniprot entry name :
TSPOA_HUMAN
sequence :
RDNHGWRGGRRLPE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Colon shows strong cytoplasm staining of absorptive cells. Recommended concentration, 2-4ug/ml. Western Blot: Approx 17kDa band observed in Human Breast cancer lysates (calculated MW of 18.8kDa according to NP_000705.2). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-RDNHGWRGGRRLPE, from the C Terminus of the protein sequence according to NP_000705.2. Corresponding Immunizing Peptide: Catalog #MBS425814
other info2 :
Important Note: This antibody is expected to recognise one isoform (NP_000705.2) only.
ncbi acc num :
NP_000705.2
ncbi gb acc num :
NM_000714.5
ncbi mol weight :
10,537 Da
ncbi pathways :
HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462
ncbi summary :
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]