catalog number :
MBS421385
products full name :
Goat anti-Engrailed-2 Antibody
products short name :
Engrailed-2
products name syn :
Engrailed-2; engrailed homolog 2; EN2; AUTS1; Engrailed-2; engrailed homolog 2; EN2; AUTS1
other names :
homeobox protein engrailed-2; Homeobox protein engrailed-2; homeobox protein engrailed-2; hu-En-2; engrailed homolog 2; homeobox protein en-2; engrailed homeobox 2
other gene names :
EN2; EN2; Homeobox protein en-2; Hu-En-2
uniprot entry name :
HME2_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
NHSTTAKEGKSDSE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx. 30kDa band observed in Mouse and Rat Brain lysates (calculated MW of 34.2kDa according to Human NP_001418.2 and of 33.8kDa according to Mouse NP_034264.1 and of 33.7kDa according to Rat NP_001102684.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-NHSTTAKEGKSDSE, from the C Terminus of the protein sequence according to NP_001418.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425896
ncbi acc num :
NP_001418.2
ncbi gb acc num :
NM_001427.3
ncbi mol weight :
34,211 Da
ncbi summary :
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]