antibody

Goat anti-Activin receptor-like kinase 1 Antibody

MBS421383

0.1 mg

290 USD

polyclonal

goat

nonconjugated

western blot, enzyme immunoassay

Antibody

Goat anti-Activin receptor-like kinase 1 Antibody

Activin receptor-like kinase 1

ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; ACVRLK1; activin A receptor type II-like 1; Activin A receptor; type II-like kinase 1; ALK1; TSR-I; TGF-B superfamily receptor type I; activin A receptor; type II-like kinase 1; serine/threonine-protein kinase receptor R3; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; ACVRLK1; activin A receptor type II-like 1; Activin A receptor, type II-like kinase 1; ALK1; TSR-I; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 1; serine/threonine-protein kinase receptor R3

serine/threonine-protein kinase receptor R3; Serine/threonine-protein kinase receptor R3; serine/threonine-protein kinase receptor R3; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 1; activin A receptor type II-like 1; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I

ACVRL1

ACVRL1; ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; ACVRLK1; ALK1; SKR3; ALK-1; TSR-I

ACVL1_HUMAN

Polyclonal

Goat

Human

503

KISNSPEKPKVIQ

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Approx 60kDa band observed in lysates of cell line MCF7 (calculated MW of 56.1kDa according to NP_000011.2). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: C Terminus. Immunogen: Peptide with sequence C-KISNSPEKPKVIQ, from the C Terminus of the protein sequence according to NP_000011.2; NP_001070869.1. Corresponding Immunizing Peptide: Catalog #MBS425741

Important Note: Please note that this product is not to be confused with the similarly named ALK (anaplastic lymphoma kinase, GeneID 238). Reported variant represent identical protein: NP_000011.2; NP_001070869.1

116734712

NP_000011.2

NM_000020.2

56,124 Da

ALK1 Pathway 137985!!ALK1 Signaling Events Pathway 137968!!Id Signaling Pathway 198871!!TGF-beta Receptor Signaling Pathway 198774

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD