product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-TRPC6 Antibody
catalog :
MBS421378
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, dog, cow
application :
western blot, flow cytometry, FACS, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS421378
products type :
Antibody
products full name :
Goat anti-TRPC6 Antibody
products short name :
TRPC6
products name syn :
TRPC6; transient receptor potential cation channel; subfamily C; member 6; HGNC:12338; TRP6; transient receptor potential channel 6; FLJ11098; FLJ14863; FSGS2; TRP6; Goat Anti-TRPC6 (C-term); TRPC6; transient receptor potential cation channel, subfamily C, member 6; HGNC:12338; TRP6; transient receptor potential channel 6; FLJ11098; FLJ14863; FSGS2; TRP6
other names :
short transient receptor potential channel 6; Short transient receptor potential channel 6; short transient receptor potential channel 6; TRP-6; transient receptor protein 6; focal segmental glomerulosclerosis 2; transient receptor potential cation channel, subfamily C, member 6; Transient receptor protein 6; TRP-6
products gene name :
TRPC6
other gene names :
TRPC6; TRPC6; TRP6; FSGS2; TRP6; TrpC6; TRP-6
uniprot entry name :
TRPC6_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Dog, Pig, Cow
sequence length :
931
sequence :
EKLSMEPNQEETN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Flow Cytometry (FC/FACS), Western Blot (WB)
app notes :
Western Blot: Preliminary experiments gave an approx 80kDa band in Human Spleen and Testis lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 106kDa according to NP_004612.2. The 80kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:2000. Flow cytometry: This antibody has been proven to specifically react to TRPC6 in FC.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-EKLSMEPNQEETN, from the C Terminus of the protein sequence according to NP_004612.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428146
ncbi gi num :
5730102
ncbi acc num :
NP_004612.2
ncbi gb acc num :
NM_004621.5
ncbi mol weight :
100,106 Da
ncbi pathways :
Axon Guidance Pathway 105688!!Developmental Biology Pathway 477129!!EPO Signaling Pathway 138051!!Effects Of PIP2 Hydrolysis Pathway 106044!!Elevation Of Cytosolic Ca2+ Levels Pathway 106047!!Endothelins Pathway 137958!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Hemostasis Pathway 106028
ncbi summary :
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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