catalog number :
MBS421377
products full name :
Goat anti-WIPF1 Antibody
products short name :
WIPF1
products name syn :
WIPF1; WAS/WASL interacting protein family; member 1; MGC111041; PRPL-2; WASPIP; WIP; Wiskott-Aldrich syndrome protein interacting protein; WIPF1; WAS/WASL interacting protein family, member 1; MGC111041; PRPL-2; WASPIP; WIP; Wiskott-Aldrich syndrome protein interacting protein
other names :
WAS/WASL-interacting protein family member 1; WAS/WASL-interacting protein family member 1; WAS/WASL-interacting protein family member 1; protein PRPL-2; WASP-interacting protein; Wiskott-Aldrich syndrome protein interacting protein; WAS/WASL interacting protein family, member 1; Protein PRPL-2; Wiskott-Aldrich syndrome protein-interacting protein; WASP-interacting protein
products gene name :
WIPF1
other gene names :
WIPF1; WIPF1; WIP; PRPL-2; WASPIP; WASPIP; WIP; WASP-interacting protein
uniprot entry name :
WIPF1_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
KLARNESRSGSNRRE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx. 55kDa band observed in Human Lymph Node, Spleen and Tonsil lysates (calculated MW of 51.3kDa according to NP_003378.3 and NP_001070737.1). In transfected HEK293 transiently expressing WIPF1 a band of approx. 55kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.03-0.1ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-KLARNESRSGSNRRE, from the C Terminus of the protein sequence according to NP_003378.3; NP_001070737.1. Corresponding Immunizing Peptide: Catalog #MBS425822
other info2 :
Important Note: Both variants represent identical proteins
ncbi acc num :
NP_003378.3
ncbi gb acc num :
NM_003387.4
ncbi mol weight :
36,426 Da
ncbi pathways :
Fc-epsilon Receptor I Signaling In Mast Cells Pathway 138050!!Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway 771577!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway 771579
ncbi summary :
This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]