This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-LXR beta / NR1H2 Antibody
catalog :
MBS421375
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS421375
products type :
Antibody
products full name :
Goat anti-LXR beta / NR1H2 Antibody
products short name :
LXR beta/NR1H2
products name syn :
NR1H2; LXR-b; NER; UNR; NER-I; RIP15; nuclear receptor subfamily 1; group H; member 2; ubiquitously-expressed nuclear receptor; LXRB; LX receptor beta; liver X receptor beta; liver X receptor-beta; nuclear orphan receptor LXR-beta; oxysterols receptor LXR-beta; steroid hormone-nuclear receptor NER; NR1H2; LXR-b; NER; UNR; NER-I; RIP15; nuclear receptor subfamily 1, group H, member 2; ubiquitously-expressed nuclear receptor; LXRB; LX receptor beta; liver X receptor beta; liver X receptor-beta; nuclear orphan receptor LXR-beta; oxysterols receptor LXR-beta; steroid hormone-nuclear receptor NER
other names :
oxysterols receptor LXR-beta isoform 1; Oxysterols receptor LXR-beta; oxysterols receptor LXR-beta; LX receptor beta; nuclear receptor NER; liver X nuclear receptor beta; nuclear orphan receptor LXR-beta; steroid hormone-nuclear receptor NER; ubiquitously-expressed nuclear receptor; nuclear receptor subfamily 1, group H, member 2; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; Ubiquitously-expressed nuclear receptor
products gene name :
NR1H2
other gene names :
NR1H2; NR1H2; NER; UNR; LXRB; LXR-b; NER-I; RIP15; LXRB; NER; UNR
uniprot entry name :
NR1H2_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog
sequence length :
461
sequence :
SSPTTSSLDTPLPGC
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Spleen shows nucleolar staining. Recommended concentration, 1-2ug/ml. Western Blot: Experiments gave a band at approx 80kDa and a weak band at appr. 60-kDa in human bone marrow lysate after 1ug/ml antibody staining. These bands correspond to earlier findings with different antibodies (PMID: 12393874-60kDa and other unpublished antibodies-80kDa). This protein has a calculated MW of 51.0kDa according to NP_009052. Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence SSPTTSSLDTPLPGC, from the N Terminus of the protein sequence according to NP_009052.3. Corresponding Immunizing Peptide: Catalog #MBS426476
other info2 :
Important Note: Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.
ncbi gi num :
85362735
ncbi acc num :
NP_009052.3
ncbi gb acc num :
NM_007121.5
ncbi mol weight :
39,920 Da
ncbi pathways :
Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!Nuclear Receptor Transcription Pathway 105979!!Nuclear Receptors Pathway 198848!!SREBP Signalling Pathway 219802
ncbi summary :
The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!