catalog number :
MBS421362
products full name :
Goat anti-SCAP2 / PRAP Antibody
products short name :
SCAP2/PRAP
products name syn :
SKAP2; SCAP2; PRAP; src family associated phosphoprotein 2; MGC10411; MGC33304; RA70; SAPS; SCAP2; SKAP-HOM; SKAP55R; Fyn-associated phosphoprotein SKAP55 homologue; Pyk2/RAFTK-associated protein; src family associated phosphoprotein 2; src kinase-associated phosphoprotein of 55-related protein; src-associated adaptor protein; SKAP2; SCAP2; PRAP; src family associated phosphoprotein 2; MGC10411; MGC33304; RA70; SAPS; SCAP2; SKAP-HOM; SKAP55R; Fyn-associated phosphoprotein SKAP55 homologue; Pyk2/RAFTK-associated protein; src family associated phosphoprotein 2; src kinase-associated phosphoprotein of 55-related protein; src-associated adaptor protein
other names :
src kinase-associated phosphoprotein 2; Src kinase-associated phosphoprotein 2; src kinase-associated phosphoprotein 2; SKAP-55HOM; SKAP55 homolog; Pyk2/RAFTK-associated protein; src-associated adaptor protein; retinoic acid-induced protein 70; src family associated phosphoprotein 2; src family-associated phosphoprotein 2; Fyn-associated phosphoprotein SKAP55 homologue; src-associated adapter protein with PH and SH3 domains; src kinase-associated phosphoprotein 55-related protein; src kinase-associated phosphoprotein of 55-related protein; src kinase associated phosphoprotein 2; Pyk2/RAFTK-associated protein; Retinoic acid-induced protein 70; SKAP55 homolog; SKAP-55HOM; SKAP-HOM; Src family-associated phosphoprotein 2; Src kinase-associated phosphoprotein 55-related protein; Src-associated adapter protein with PH and SH3 domains
products gene name :
SKAP2
other gene names :
SKAP2; SKAP2; PRAP; RA70; SAPS; SCAP2; SKAP55R; SKAP-HOM; PRAP; RA70; SAPS; SCAP2; SKAP55R; SKAP-55HOM; SKAP-HOM
uniprot entry name :
SKAP2_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
GLVPKAYIMEMYDI
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 38kDa band observed in lysates of cell line Jurkat (calculated MW of 41.2kDa according to NP_003921.2). In transfected HEK293 transiently expressing SKAP2 a band of approx. 45kDa is observed. This band is not observed in the non-transfected HEK293. The calculated Recommended concentration: 0.5-2ug/ml.
An additional band of unknown identity was also consistently observed in Jurkat at 28kDa. This band was successfully blocked by incubation with the immunising peptide. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-GLVPKAYIMEMYDI, from the C Terminus of the protein sequence according to NP_003921.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425543
ncbi acc num :
NP_003921.2
ncbi gb acc num :
NM_003930.3
ncbi mol weight :
41,217 Da
ncbi pathways :
Cell-Cell Communication Pathway 477132!!Signal Regulatory Protein (SIRP) Family Interactions Pathway 187209
ncbi summary :
The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation. [provided by RefSeq, Jul 2008]