This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-SMAD4 / MADH4 Antibody
catalog :
MBS421353
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, immunoprecipitation, enzyme immunoassay
product information
catalog number :
MBS421353
products type :
Antibody
products full name :
Goat anti-SMAD4 / MADH4 Antibody
products short name :
SMAD4/MADH4
products name syn :
MADH4; SMAD4; JIP; DPC4; MAD; mothers against decapentaplegic homolog 4 (Drosophila); Mothers against decapentaplegic; Drosophila; homolog of; 4; MAD (mothers against decapentaplegic; Drosophila) homolog 4; SMAD family member 4; OTTHUMP00000163548; SMAD; mothers against DPP homolog 4; deleted in pancreatic carcinoma locus 4; mothers against decapentaplegic homolog 4; MADH4; SMAD4; JIP; DPC4; MAD, mothers against decapentaplegic homolog 4 (Drosophila); Mothers against decapentaplegic, Drosophila, homolog of, 4; MAD (mothers against decapentaplegic, Drosophila) homolog 4; SMAD family member 4; OTTHUMP00000163548; SMAD, mothers against DPP homolog 4; deleted in pancreatic carcinoma locus 4; mothers against decapentaplegic homolog 4
other names :
mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic homolog 4; MAD homolog 4; SMAD, mothers against DPP homolog 4; deleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; mothers against decapentaplegic, Drosophila, homolog of, 4; SMAD family member 4; Deletion target in pancreatic carcinoma 4; SMAD family member 4; SMAD 4; Smad4; hSMAD4
products gene name :
SMAD4
other gene names :
SMAD4; SMAD4; JIP; DPC4; MADH4; MYHRS; DPC4; MADH4; MAD homolog 4; Mothers against DPP homolog 4; SMAD 4; Smad4; hSMAD4
uniprot entry name :
SMAD4_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog, Pig Cow
sequence length :
552
sequence :
HTMPIADPQPLD
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP)
app notes :
Western Blot: Approx 60-65kDa band seen in mouse NIH-3T3 cell lysate. Recommended for use at 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000. Immunoprecipitation:This antibody was deemed fit for IP under native conditions (observations from anonymous customer).
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-HTMPIADPQPLD, from the C Terminus of the protein sequence according to NP_005350.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425590
ncbi gi num :
4885457
ncbi acc num :
NP_005350.1
ncbi gb acc num :
NM_005359.5
ncbi mol weight :
60,439 Da
ncbi pathways :
ALK1 Signaling Events Pathway 137968!!ALK2 Signaling Events Pathway 137983!!Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Androgen Receptor Signaling Pathway 198806!!BMP Signalling Pathway 545370!!BMP Receptor Signaling Pathway 137948!!BMP Signalling And Regulation Pathway 198910!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054
ncbi summary :
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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