catalog number :
MBS421322
products full name :
Goat anti-SORBS1 / Ponsin (C Terminus) Antibody
products short name :
SORBS1/Ponsin
products name syn :
SORBS1; PONSIN; sorbin and SH3 domain containing 1; CAP; SH3D5; SORB1; SH3P12; ponsin; sh3p12; FLJ12406; KIAA1296; DKFZP586P1422; DKFZp451C066; SH3-domain protein 5 (ponsin); FLAF2; FLJ12406; R85FL; Fas-ligand associated factor 2; c-Cbl associated protein; DKFZp586P1422; OTTHUMP00000020142; OTTHUMP00000020143; OTTHUMP00000020144; OTTHUMP00000020145; ponsin; Goat Anti-SORBS1/ponsin (internal region); SORBS1; PONSIN; sorbin and SH3 domain containing 1; CAP; SH3D5; SORB1; SH3P12; ponsin; sh3p12; FLJ12406; KIAA1296; DKFZP586P1422; DKFZp451C066; SH3-domain protein 5 (ponsin); FLAF2; FLJ12406; R85FL; Fas-ligand associated factor 2; c-Cbl associated protein; DKFZp586P1422; OTTHUMP00000020142; OTTHUMP00000020143; OTTHUMP00000020144; OTTHUMP00000020145; ponsin
other names :
sorbin and SH3 domain-containing protein 1 isoform 1; Sorbin and SH3 domain-containing protein 1; sorbin and SH3 domain-containing protein 1; SORBS1; ponsin; SH3 domain protein 5; c-Cbl associated protein; Fas-ligand associated factor 2; sorbin and SH3 domain containing 1; Ponsin; SH3 domain protein 5; SH3P12; c-Cbl-associated protein; CAP
products gene name :
SORBS1
other gene names :
SORBS1; SORBS1; CAP; FLAF2; R85FL; SH3D5; SORB1; SH3P12; CAP
uniprot entry name :
SRBS1_HUMAN
reactivity :
Human, Mouse, Rat, Pig
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Skeletal Muscle shows spotty staining on muscle fibres in longitudinal section. Recommended concentration, 2.5ug/ml. Data obtained from a previous batch. Western Blot: No signal obtained yet but low background observed in human heart and 293 lysates at up to 2ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-GTFPGNYVKPLYL, from the C Terminus of the protein sequence according to NP_006425.2; NP_056200.1; NP_001030126.1; NP_001030127.1; NP_001030128.1; NP_079267.1; NP_001030129.1. Corresponding Immunizing Peptide: Catalog #MBS428597
other info2 :
Important Note: This antibody is expected to recognize all seven reported isoforms (NP_006425.2, NP_056200.1, NP_001030126.1, NP_001030127.1, NP_001030128.1, NP_079267.1 and NP_001030129.1).
ncbi acc num :
NP_006425.2
ncbi gb acc num :
NM_006434.2
ncbi mol weight :
143,741 Da
ncbi pathways :
Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Insulin Pathway 138026!!Insulin Signaling Pathway 198845!!Insulin Signaling Pathway 83090!!Insulin Signaling Pathway 501!!Integrin-mediated Cell Adhesion Pathway 198816!!Muscle Contraction Pathway 106261!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450
ncbi summary :
This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]