product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-PAR6alpha / PARD6A Antibody
catalog :
MBS421305
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421305
products type :
Antibody
products full name :
Goat anti-PAR6alpha / PARD6A Antibody
products short name :
PAR6alpha/PARD6A
products name syn :
PARD6A; PAR6alpha; PAR-6; TAX40; PAR-6A; TIP-40; par-6 partitioning defective 6 homolog alpha (C.elegans); Tax interaction protein 40; par-6 (partitioning defective 6; C.elegans) homolog alpha; PAR6; PAR6C; Tax-interacting protein 40; par-6 partitioning defective 6 homolog alpha; partitioning defective-6 homolog alpha; partitioning-defective protein 6; PARD6A; PAR6alpha; PAR-6; TAX40; PAR-6A; TIP-40; par-6 partitioning defective 6 homolog alpha (C.elegans); Tax interaction protein 40; par-6 (partitioning defective 6, C.elegans) homolog alpha; PAR6; PAR6C; Tax-interacting protein 40; par-6 partitioning defective 6 homolog alpha; partitioning defective-6 homolog alpha; partitioning-defective protein 6
other names :
partitioning defective 6 homolog alpha isoform 1; Partitioning defective 6 homolog alpha; partitioning defective 6 homolog alpha; PAR-6 alpha; Tax-interacting protein 40; tax interaction protein 40; partitioning-defective protein 6; partitioning defective-6 homolog alpha; par-6 partitioning defective 6 homolog alpha; par-6 family cell polarity regulator alpha; PAR6C; Tax interaction protein 40; TIP-40
products gene name :
PARD6A
other gene names :
PARD6A; PARD6A; PAR6; PAR6C; TAX40; PAR-6A; TIP-40; PAR6alpha; PAR6A; PAR-6; PAR-6 alpha; PAR-6A; TIP-40
uniprot entry name :
PAR6A_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human
sequence length :
346
sequence :
GSRIRGDGSGFSL
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Pancreas, shows strong cytoplasmic staining in rare cells of intralobular ducts. Recommended concentration, 10ug/ml. Also tested in paraffin embedded Human Heart where it shows speckled staining on myocardial fibres in transverse section. Recommended concentration, 5-10ug/ml. Western Blot: Preliminary experiments gave no signal but low background in Human Brain and Pancreas extracts at up to 1ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-GSRIRGDGSGFSL, from the C Terminus of the protein sequence according to NP_058644.1; NP_001032358.1. Corresponding Immunizing Peptide: Catalog #MBS425370
other info2 :
Important Note: This antibody is expected to recognise both reported isoforms (NP_058644.1; NP_001032358.1).
ncbi gi num :
8394417
ncbi acc num :
NP_058644.1
ncbi gb acc num :
NM_016948.2
ncbi mol weight :
37,317 Da
ncbi pathways :
Asymmetric Localization Of PCP Proteins Pathway 941396!!CDC42 Signaling Events Pathway 137994!!Cell Junction Organization Pathway 160966!!Cell-Cell Communication Pathway 477132!!Cell-cell Junction Organization Pathway 119532!!Disease Pathway 530764!!Endocytosis Pathway 102279!!Endocytosis Pathway 102181!!Hippo Signaling Pathway 749777!!Hippo Signaling Pathway 750388
ncbi summary :
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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