product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-FOXA2 / HNF3B Antibody
catalog :
MBS421289
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421289
products type :
Antibody
products full name :
Goat anti-FOXA2 / HNF3B Antibody
products short name :
FOXA2/HNF3B
products name syn :
FOXA2; HNF3B; forkhead box A2; TCF3B; MGC19807; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3; beta; FOXA2; HNF3B; forkhead box A2; TCF3B; MGC19807; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3, beta
other names :
hepatocyte nuclear factor 3-beta isoform 1; Hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor 3-beta; HNF-3B; TCF-3B; HNF-3-beta; forkhead box protein A2; transcription factor 3B; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3, beta; forkhead box A2; Forkhead box protein A2; Transcription factor 3B; TCF-3B
products gene name :
FOXA2
other gene names :
FOXA2; FOXA2; HNF3B; TCF3B; HNF3B; TCF3B; HNF-3-beta; HNF-3B; TCF-3B
uniprot entry name :
FOXA2_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat
sequence length :
463
sequence :
GVYSRPIMNSS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 60kDa band observed in Human Liver lysates (calculated MW of 48.3kDa according to NP_068556.1and NP_710141.1). The observed molecular weight corresponds to earlier findings in literature (Wang et al, J Biol Chem. 2002 May 17;277(20):17564-70.; PMID: 11875061). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-GVYSRPIMNSS, from the C Terminus of the protein sequence according to NP_068556.2; NP_710141.1. Corresponding Immunizing Peptide: Catalog #MBS426307
other info2 :
Important Note: This antibody is expected to recognise both reported isoforms.
products references :
Nakamura K, Moore R, Negishi M, Sueyoshi T.; Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver.; J Biol Chem. 2007 Mar 30; 282(13):9768-76.; Pubmed 17267396
ncbi gi num :
194394143
ncbi acc num :
NP_068556.2
ncbi gb acc num :
NM_021784.4
ncbi mol weight :
48,907 Da
ncbi pathways :
Cardiac Progenitor Differentiation Pathway 712094!!Developmental Biology Pathway 477129!!FOXA Transcription Factor Networks Pathway 138065!!FOXA1 Transcription Factor Network Pathway 137979!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Heart Development Pathway 198802!!Hedgehog Signaling Events Mediated By Gli Proteins Pathway 137912!!Maturity Onset Diabetes Of The Young Pathway 83096!!Maturity Onset Diabetes Of The Young Pathway 508!!Regulation Of Beta-cell Development Pathway 106328
ncbi summary :
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
size :
0.1 mg
price :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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